Complete Response of Synchronous Liver Metastasis in a Pancreatic Ductal Adenocarcinoma, When Surgery Could Represent a Therapeutic Option
المؤلفون المشاركون
Argentiero, Antonella
Calabrese, Angela
Sciacovelli, Angela Monica
Delcuratolo, Sabina
Solimando, Antonio Giovanni
Brunetti, Oronzo
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-10-10
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Metastatic pancreatic ductal adenocarcinoma (PDAC) is characterized by poor prognosis and short survival.
Today, the use of new polytherapeutic regimens increases clinical outcome of these patients opening new clinical scenario.
A crucial issue related to the actual improvement achieved with these new regimens is represented by the occasional possibility to observe a radiological complete response of metastatic lesions in patients with synchronous primary tumor.
What could be the best therapeutic management of these patients? Could surgery represent an indication? Herein, we reported a case of a patient with PDAC of the head with multiple liver metastases, who underwent first-line chemotherapy with mFOLFIRINOX.
After 10 cycles, he achieved a complete radiological response of liver metastases and a partial response of pancreatic lesion.
A duodenocephalopancreasectomy was performed.
Due to liver a lung metastases after 8 months from surgery, a second-line therapy was started with a disease-free survival and overall survival of 8 months and 45 months, respectively.
Improvement in the molecular characterization of PDAC could help in the selection of patients suitable for multimodal treatments.
This trial is registered with NCT02892305 and NCT00855634.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Argentiero, Antonella& Calabrese, Angela& Sciacovelli, Angela Monica& Delcuratolo, Sabina& Solimando, Antonio Giovanni& Brunetti, Oronzo. 2020. Complete Response of Synchronous Liver Metastasis in a Pancreatic Ductal Adenocarcinoma, When Surgery Could Represent a Therapeutic Option. Canadian Journal of Gastroenterology and Hepatology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1139038
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Argentiero, Antonella…[et al.]. Complete Response of Synchronous Liver Metastasis in a Pancreatic Ductal Adenocarcinoma, When Surgery Could Represent a Therapeutic Option. Canadian Journal of Gastroenterology and Hepatology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1139038
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Argentiero, Antonella& Calabrese, Angela& Sciacovelli, Angela Monica& Delcuratolo, Sabina& Solimando, Antonio Giovanni& Brunetti, Oronzo. Complete Response of Synchronous Liver Metastasis in a Pancreatic Ductal Adenocarcinoma, When Surgery Could Represent a Therapeutic Option. Canadian Journal of Gastroenterology and Hepatology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1139038
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139038
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر