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Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children
المؤلفون المشاركون
Kim, Shinuk
Cho, Jinkyung
Park, Soo Hyun
Hong, Haeryun
Kang, H.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-31
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
This study investigated the association between insulin resistance (IR) and metabolic syndrome (MetS) in children.
Methods.
A cross-sectional study involving 1036 healthy children aged between 7 and 13 years was conducted.
Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated as an index of IR.
Participants were classified according to the HOMA-IR quartiles.
Results.
Incremental, linear trends were found in age (p<0.001), body mass index (BMI) (p<0.001), body fat (p<0.001), waist circumference (p<0.001), resting blood pressures (BP) (p<0.001), triglycerides (TG) (p<0.001), total cholesterol (TC) (p<0.001), high density lipoprotein-cholesterol (HDL-C) (p<0.001), FBG (p<0.001), and insulin (<0.001) according to incremental HOMA-IR categories (from the 1st to 4th quartile).
Compared with children in the 1st HOMA-IR quartile, children in the 4th HOMA-IR quartile had significantly higher odd ratios (ORs) of abnormalities in systolic (p=0.051) and diastolic BP (p=0.005), FBG (p<0.001), TG (p<0.001), TC (p=0.016), and HDL-C (p=0.006) even after adjustments for age, gender, BMI, and body fat percentage.
Children in the 3rd HOMA-IR quartile had significant abnormalities in FBG (p<0.001), TG (p=0.001), and HDL-C (p=0.010) even after adjustments for the covariates.
Conclusion.
The current findings suggest that IR is significantly associated with the clustering of MetS risk factors in children in Korea.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cho, Jinkyung& Hong, Haeryun& Park, Soo Hyun& Kim, Shinuk& Kang, H.. 2017. Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139248
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cho, Jinkyung…[et al.]. Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1139248
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cho, Jinkyung& Hong, Haeryun& Park, Soo Hyun& Kim, Shinuk& Kang, H.. Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139248
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139248
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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