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Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children
Joint Authors
Kim, Shinuk
Cho, Jinkyung
Park, Soo Hyun
Hong, Haeryun
Kang, H.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
This study investigated the association between insulin resistance (IR) and metabolic syndrome (MetS) in children.
Methods.
A cross-sectional study involving 1036 healthy children aged between 7 and 13 years was conducted.
Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated as an index of IR.
Participants were classified according to the HOMA-IR quartiles.
Results.
Incremental, linear trends were found in age (p<0.001), body mass index (BMI) (p<0.001), body fat (p<0.001), waist circumference (p<0.001), resting blood pressures (BP) (p<0.001), triglycerides (TG) (p<0.001), total cholesterol (TC) (p<0.001), high density lipoprotein-cholesterol (HDL-C) (p<0.001), FBG (p<0.001), and insulin (<0.001) according to incremental HOMA-IR categories (from the 1st to 4th quartile).
Compared with children in the 1st HOMA-IR quartile, children in the 4th HOMA-IR quartile had significantly higher odd ratios (ORs) of abnormalities in systolic (p=0.051) and diastolic BP (p=0.005), FBG (p<0.001), TG (p<0.001), TC (p=0.016), and HDL-C (p=0.006) even after adjustments for age, gender, BMI, and body fat percentage.
Children in the 3rd HOMA-IR quartile had significant abnormalities in FBG (p<0.001), TG (p=0.001), and HDL-C (p=0.010) even after adjustments for the covariates.
Conclusion.
The current findings suggest that IR is significantly associated with the clustering of MetS risk factors in children in Korea.
American Psychological Association (APA)
Cho, Jinkyung& Hong, Haeryun& Park, Soo Hyun& Kim, Shinuk& Kang, H.. 2017. Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139248
Modern Language Association (MLA)
Cho, Jinkyung…[et al.]. Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1139248
American Medical Association (AMA)
Cho, Jinkyung& Hong, Haeryun& Park, Soo Hyun& Kim, Shinuk& Kang, H.. Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139248
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139248