Orthostatic Intolerance and Postural Orthostatic Tachycardia Syndrome in Joint Hypermobility SyndromeEhlers-Danlos Syndrome, Hypermobility Type: Neurovegetative Dysregulation or Autonomic Failure?
المؤلفون المشاركون
Celletti, Claudia
Camerota, Filippo
Castori, Marco
Censi, Federica
Gioffrè, Laura
Calcagnini, Giovanni
Strano, Stefano
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-12
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Joint hypermobility syndrome/Ehlers-Danlos syndrome, hypermobility type (JHS/EDS-HT), is a hereditary connective tissue disorder mainly characterized by generalized joint hypermobility, skin texture abnormalities, and visceral and vascular dysfunctions, also comprising symptoms of autonomic dysfunction.
This study aims to further evaluate cardiovascular autonomic involvement in JHS/EDS-HT by a battery of functional tests.
Methods.
The response to cardiovascular reflex tests comprising deep breathing, Valsalva maneuver, 30/15 ratio, handgrip test, and head-up tilt test was studied in 35 JHS/EDS-HT adults.
Heart rate and blood pressure variability was also investigated by spectral analysis in comparison to age and sex healthy matched group.
Results.
Valsalva ratio was normal in all patients, but 37.2% of them were not able to finish the test.
At tilt, 48.6% patients showed postural orthostatic tachycardia, 31.4% orthostatic intolerance, 20% normal results.
Only one patient had orthostatic hypotension.
Spectral analysis showed significant higher baroreflex sensitivity values at rest compared to controls.
Conclusions.
This study confirms the abnormal cardiovascular autonomic profile in adults with JHS/EDS-HT and found the higher baroreflex sensitivity as a potential disease marker and clue for future research.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Celletti, Claudia& Camerota, Filippo& Castori, Marco& Censi, Federica& Gioffrè, Laura& Calcagnini, Giovanni…[et al.]. 2017. Orthostatic Intolerance and Postural Orthostatic Tachycardia Syndrome in Joint Hypermobility SyndromeEhlers-Danlos Syndrome, Hypermobility Type: Neurovegetative Dysregulation or Autonomic Failure?. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139374
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Celletti, Claudia…[et al.]. Orthostatic Intolerance and Postural Orthostatic Tachycardia Syndrome in Joint Hypermobility SyndromeEhlers-Danlos Syndrome, Hypermobility Type: Neurovegetative Dysregulation or Autonomic Failure?. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1139374
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Celletti, Claudia& Camerota, Filippo& Castori, Marco& Censi, Federica& Gioffrè, Laura& Calcagnini, Giovanni…[et al.]. Orthostatic Intolerance and Postural Orthostatic Tachycardia Syndrome in Joint Hypermobility SyndromeEhlers-Danlos Syndrome, Hypermobility Type: Neurovegetative Dysregulation or Autonomic Failure?. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139374
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139374
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر