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Evaluation of Risk Factors for Vertebral Compression Fracture after Carbon-Ion Radiotherapy for Primary Spinal and Paraspinal Sarcoma
المؤلفون المشاركون
Nakashima, Yasuharu
Matsumoto, Yoshihiro
Fukushi, Jun-ichi
Kawaguchi, Ken-ichi
Setsu, Nokitaka
IIda, Keiichiro
Endo, Makoto
Okada, Seiji
Bekki, Hirofumi
Shinoto, Makoto
Imai, Reiko
Kamada, Tadashi
Shioyama, Yoshiyuki
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-26
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background and Purpose.
Carbon-ion radiotherapy (C-ion RT) was effective therapy for inoperable spinal and paraspinal sarcomas.
However, a significant adverse event following radiotherapies is vertebral compression fractures (VCFs).
In this study, we investigated the incidence of and risk factors for post-C-ion RT VCFs in patients with spinal or paraspinal sarcomas.
Material and Methods.
Thirty consecutive patients with spinal or paraspinal sarcomas treated with C-ion RT were retrospectively reviewed.
Various clinical parameters and the Spinal Instability Neoplastic Score (SINS) were used to evaluate the risk factors for post-C-ion RT VCFs.
Results.
The overall incidence of VCFs was 23% (median time: 7 months).
Patients with VCFs showed a markedly higher SINS score (median value, 9 points) than those without VCF (5 points).
The area under the receiver operating characteristic curve for the SINS score was 0.88, and the optimum SINS cut-off score was 8 points.
The cumulative incidence of VCFs at 1 year was 9% for patients with a SINS score under 8 points, versus 80% for those with a SINS score of 8 points or higher (p<0.0001).
Conclusions.
In patients with a SINS score of 8 points or higher, referral to a spine surgeon for stabilization and multidisciplinary discussion is appropriate.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Matsumoto, Yoshihiro& Shinoto, Makoto& Endo, Makoto& Setsu, Nokitaka& IIda, Keiichiro& Fukushi, Jun-ichi…[et al.]. 2017. Evaluation of Risk Factors for Vertebral Compression Fracture after Carbon-Ion Radiotherapy for Primary Spinal and Paraspinal Sarcoma. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139545
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Matsumoto, Yoshihiro…[et al.]. Evaluation of Risk Factors for Vertebral Compression Fracture after Carbon-Ion Radiotherapy for Primary Spinal and Paraspinal Sarcoma. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1139545
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Matsumoto, Yoshihiro& Shinoto, Makoto& Endo, Makoto& Setsu, Nokitaka& IIda, Keiichiro& Fukushi, Jun-ichi…[et al.]. Evaluation of Risk Factors for Vertebral Compression Fracture after Carbon-Ion Radiotherapy for Primary Spinal and Paraspinal Sarcoma. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139545
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139545
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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