Cognitive Impairment in Relapsing-Remitting Multiple Sclerosis Patients with Very Mild Clinical Disability
المؤلفون المشاركون
Fabrizio, Vernieri
Curcio, Giuseppe
Migliore, S.
Ghazaryan, A.
Simonelli, I.
Squitieri, F.
Landi, D.
Palmieri, M. G.
Filippi, M. M.
Moffa, F.
Pasqualetti, Patrizio
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-15
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Cognitive dysfunction affects 40–65% of multiple sclerosis (MS) patients and can occur in the early stages of the disease.
This study aimed to explore cognitive functions by means of the Italian version of the minimal assessment of cognitive function in MS (MACFIMS) in relapsing-remitting MS (RRMS) patients with very mild clinical disability to identify the primarily involved cognitive functions.
Ninety-two consecutive RRMS patients with Expanded Disability Status Scale (EDSS) scores ≤ 2.5 and forty-two healthy controls (HC) were investigated.
Our results show that 51.1% of MS patients have cognitive dysfunction compared to HC.
An impairment of verbal and visual memory, working memory, and executive functions was found in the RRMS group.
After subgrouping RRMS by EDSS, group 1 (EDSS ≤ 1.5) showed involvement of verbal memory and executive functions; moreover, group 2 (2 ≤ EDSS ≤ 2.5) patients were also impaired in information processing speed and visual memory.
Our results show that utilizing a comprehensive neuropsychological assessment, approximately half of MS patients with very mild physical disability exhibit cognitive impairment with a primary involvement of prefrontal cognitive functions.
Detecting impairment of executive functions at an early clinical stage of disease could be useful to promptly enroll MS patients in targeted rehabilitation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Migliore, S.& Ghazaryan, A.& Simonelli, I.& Pasqualetti, Patrizio& Squitieri, F.& Curcio, Giuseppe…[et al.]. 2017. Cognitive Impairment in Relapsing-Remitting Multiple Sclerosis Patients with Very Mild Clinical Disability. Behavioural Neurology،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1139788
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Migliore, S.…[et al.]. Cognitive Impairment in Relapsing-Remitting Multiple Sclerosis Patients with Very Mild Clinical Disability. Behavioural Neurology No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1139788
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Migliore, S.& Ghazaryan, A.& Simonelli, I.& Pasqualetti, Patrizio& Squitieri, F.& Curcio, Giuseppe…[et al.]. Cognitive Impairment in Relapsing-Remitting Multiple Sclerosis Patients with Very Mild Clinical Disability. Behavioural Neurology. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1139788
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139788
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر