Detailed Histologic Evaluation of Eosinophilic Esophagitis in Pediatric Patients Presenting with Dysphagia or Abdominal Pain and Comparison of the Histology between the Two Groups
المؤلفون المشاركون
Gunasekaran, Thirumazhisai
Schwartz, Alan
Chu, Christopher
Ronquillo, Nemencio
Adley, Brian
Borgen, Kristina
Newberry, Robert
Berman, James
Chennuri, Rohini
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
EoE in children presents with four main symptoms.
Most common symptoms exhibited by our clinic population are dysphagia (D) and abdominal pain (AP).
Despite similar treatments, we found in an earlier study that the outcomes between these two groups were different.
Therefore, we investigated if there exist any histological differences between these groups that could further our knowledge of EoE.
Aim.
To compare esophageal histology in detail, apart from the eosinophil count, between EoE-D and EoE-AP.
Method.
Biopsies of patients with EoE-D and EoE-AP were reevaluated for 10 additional histological criteria, in addition to the eosinophil count.
Results.
Both groups had 67 patients; peak mean eosinophil was 33.9 and 31.55 for EoE-D and EoE-AP (p<0.05).
Eosinophilic microabscesses, superficial layering of eosinophils, and epithelial desquamation were twice as common and significant in EoE-D group than EoE-AP.
Eosinophil distribution around rete pegs was also significantly higher in EoE-D group.
The remaining criteria were numerically higher in EoE-D, but not significant, with the exception of rete peg elongation.
Conclusion.
EoE-D patients have significantly higher eosinophils compared to EoE-AP, and the level of inflammation as seen from eosinophil microabscesses, superficial layering, desquamation, and the distribution around rete pegs is significantly higher.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gunasekaran, Thirumazhisai& Chu, Christopher& Ronquillo, Nemencio& Chennuri, Rohini& Adley, Brian& Borgen, Kristina…[et al.]. 2017. Detailed Histologic Evaluation of Eosinophilic Esophagitis in Pediatric Patients Presenting with Dysphagia or Abdominal Pain and Comparison of the Histology between the Two Groups. Canadian Journal of Gastroenterology and Hepatology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141403
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gunasekaran, Thirumazhisai…[et al.]. Detailed Histologic Evaluation of Eosinophilic Esophagitis in Pediatric Patients Presenting with Dysphagia or Abdominal Pain and Comparison of the Histology between the Two Groups. Canadian Journal of Gastroenterology and Hepatology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1141403
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gunasekaran, Thirumazhisai& Chu, Christopher& Ronquillo, Nemencio& Chennuri, Rohini& Adley, Brian& Borgen, Kristina…[et al.]. Detailed Histologic Evaluation of Eosinophilic Esophagitis in Pediatric Patients Presenting with Dysphagia or Abdominal Pain and Comparison of the Histology between the Two Groups. Canadian Journal of Gastroenterology and Hepatology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141403
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1141403
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر