Superficial Myofibroblastoma in the Vulva Mimicking Aggressive Angiomyxoma: A Case Report and Review of the Literature
المؤلفون المشاركون
Peng, Wei-Xia
Wada, Ryuichi
Kure, Shoko
Fukunaga, Masaharu
Naito, Zenya
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-26
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background: Superficial myofibroblastoma (SMF) is a very rare benign mesenchymal tumor in the female lower genital tract.
Only 46 cases have been reported in the English language literature, among which only 7 cases arose in the vulva.
Sometimes SMF histologically mimics aggressive angiomyxoma (AA) in which massive myxoid change in stroma is characteristic.
We herein report a case of vulvar SMF with prominent myxoid stroma and review the literature with the emphasis on the differential diagnosis of SMF and AA.
Case presentation: a 37-year-old woman presented with a painless mass in the vulva.
Magnetic resonance imaging (MRI) showed a well-circumscribed 7 cm mass in the subcutis of the vulva.
The tumor was resected.
Histopathologically, the tumor was characterized by sparsely populated spindle-shaped cells in the fibromyxoid stroma.
Thin-walled blood vessels were detected.
Mitoses or pleomorphism was not found.
Tumor cells were positive for vimentin, ER, PgR, and desmin.
Some cells were positive for alpha-SMA and CD34.
All cells were negative for S100 protein.
Conclusions: because SMF and AA show different clinical prognoses, distinguishing SMF from AA is important.
However, SMF may share many common histological features with AA: superficial localization (above fascia), sharp borderline from adjacent tissue, expansive growth pattern; a specific vascular pattern will lead to an accurate diagnosis of SMF.
Familiarization with the histological characteristics of the two entities will help to make a prognostic prediction.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Peng, Wei-Xia& Wada, Ryuichi& Kure, Shoko& Fukunaga, Masaharu& Naito, Zenya. 2019. Superficial Myofibroblastoma in the Vulva Mimicking Aggressive Angiomyxoma: A Case Report and Review of the Literature. Case Reports in Pathology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1143381
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Peng, Wei-Xia…[et al.]. Superficial Myofibroblastoma in the Vulva Mimicking Aggressive Angiomyxoma: A Case Report and Review of the Literature. Case Reports in Pathology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1143381
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Peng, Wei-Xia& Wada, Ryuichi& Kure, Shoko& Fukunaga, Masaharu& Naito, Zenya. Superficial Myofibroblastoma in the Vulva Mimicking Aggressive Angiomyxoma: A Case Report and Review of the Literature. Case Reports in Pathology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1143381
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1143381
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر