Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl

المؤلفون المشاركون

Forget, P.
Nicolescu, Ramona
Kasongo, Laura

المصدر

Case Reports in Pediatrics

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-5، 5ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-09-08

دولة النشر

مصر

عدد الصفحات

5

التخصصات الرئيسية

الطب البشري

الملخص EN

Wilms tumor is the most frequent pediatric renal malignancy, and its usual presentation is an abdominal mass or hematuria.

Unusual presentations have also been reported, such as paraneoplastic syndromes (acquired von Willebrand disease, sudden death due to pulmonary embolism, and Cushing syndrome).

These conditions can precede, occur concomitantly, or present in a later phase of tumor development.

Precocious puberty, as paraneoplastic endocrine syndrome, has already been described in children with malignant tumors (brain, gonadal, adrenal tumors, and hepatoblastoma).

However, little is known about central precocious puberty, as paraneoplastic manifestation of nephroblastoma or secondary to its specific chemotherapy.

Here, we report a case of Wilms tumor and simultaneous precocious puberty in a 5-year-old girl.

The initial diagnosis was premature telarche, but the clinical and biological pubertal progression changed our diagnosis to idiopathic central precocious puberty.

Chemotherapy and nephrectomy were well tolerated, and we began treatment with a gonadotropin-releasing hormone agonist which showed favorable outcomes over the short term.

We highlight the need for early diagnosis and work-up in all patients of precocious puberty, in order to institute timely management.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Kasongo, Laura& Forget, P.& Nicolescu, Ramona. 2019. Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl. Case Reports in Pediatrics،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1143723

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Kasongo, Laura…[et al.]. Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl. Case Reports in Pediatrics No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1143723

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Kasongo, Laura& Forget, P.& Nicolescu, Ramona. Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl. Case Reports in Pediatrics. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1143723

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1143723