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Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl
Joint Authors
Forget, P.
Nicolescu, Ramona
Kasongo, Laura
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Wilms tumor is the most frequent pediatric renal malignancy, and its usual presentation is an abdominal mass or hematuria.
Unusual presentations have also been reported, such as paraneoplastic syndromes (acquired von Willebrand disease, sudden death due to pulmonary embolism, and Cushing syndrome).
These conditions can precede, occur concomitantly, or present in a later phase of tumor development.
Precocious puberty, as paraneoplastic endocrine syndrome, has already been described in children with malignant tumors (brain, gonadal, adrenal tumors, and hepatoblastoma).
However, little is known about central precocious puberty, as paraneoplastic manifestation of nephroblastoma or secondary to its specific chemotherapy.
Here, we report a case of Wilms tumor and simultaneous precocious puberty in a 5-year-old girl.
The initial diagnosis was premature telarche, but the clinical and biological pubertal progression changed our diagnosis to idiopathic central precocious puberty.
Chemotherapy and nephrectomy were well tolerated, and we began treatment with a gonadotropin-releasing hormone agonist which showed favorable outcomes over the short term.
We highlight the need for early diagnosis and work-up in all patients of precocious puberty, in order to institute timely management.
American Psychological Association (APA)
Kasongo, Laura& Forget, P.& Nicolescu, Ramona. 2019. Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl. Case Reports in Pediatrics،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1143723
Modern Language Association (MLA)
Kasongo, Laura…[et al.]. Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl. Case Reports in Pediatrics No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1143723
American Medical Association (AMA)
Kasongo, Laura& Forget, P.& Nicolescu, Ramona. Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl. Case Reports in Pediatrics. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1143723
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143723