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Ibrutinib Treatment through Nasogastric Tube in a Comatose Patient with Central Nervous System Localization of Mantle Cell Lymphoma
المؤلفون المشاركون
Alsuliman, Tamim
Belghoul, Maifa
Choufi, Bachra
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-08-16
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Nowadays, mantle cell lymphoma is considered to have one of the worst prognostic profiles among lymphoid malignancies.
Mantle cell lymphoma rarely affects the central nervous system (CNS) as it represents about 0.9% of diagnosis and 4% among recurrent cases.
Here, we present the case of a 69-year-old male patient who was diagnosed with mantle cell lymphoma in 2006.
The patient relapsed three times, without affecting the CNS, then was treated accordingly, and achieved complete remission three times.
Four years after his last complete remission, upon receiving his last dose of treatment, the medical team noted a rapid worsening of the patient’s neurological status followed by a deep coma state causing MCL neurological recurrence by exclusion diagnosis.
The patient then received ibrutinib via a nasogastric tube at a dose of 560 mg daily.
Two days after receiving his last dose of ibrutinib, the patient regained full consciousness, and 10 days later, he was discharged from the hospital.
The patient achieved complete remission and showed no signs of neurological damages for 24 months following his ibrutinib treatment.
We believe that the administration of ibrutinib through the nasogastric tube was a determinant factor in this patient’s remission and survival.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alsuliman, Tamim& Belghoul, Maifa& Choufi, Bachra. 2018. Ibrutinib Treatment through Nasogastric Tube in a Comatose Patient with Central Nervous System Localization of Mantle Cell Lymphoma. Case Reports in Hematology،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143899
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alsuliman, Tamim…[et al.]. Ibrutinib Treatment through Nasogastric Tube in a Comatose Patient with Central Nervous System Localization of Mantle Cell Lymphoma. Case Reports in Hematology No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1143899
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alsuliman, Tamim& Belghoul, Maifa& Choufi, Bachra. Ibrutinib Treatment through Nasogastric Tube in a Comatose Patient with Central Nervous System Localization of Mantle Cell Lymphoma. Case Reports in Hematology. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143899
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1143899
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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