A Case of Heparin-Induced Thrombocytopenia That Developed in the Therapeutic Course of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
المؤلفون المشاركون
Harada, Makoto
Ichikawa, Tohru
Kobayashi, Mamoru
Nonaka, Taketoshi
Sumi, Masahiko
Ishii, Wataru
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-22
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
Heparin-induced thrombocytopenia (HIT) causes thrombocytopenia via an immunological mechanism, resulting in severe organ injury due to arterial-venous thrombosis.
HIT often develops in hemodialysis patients owing to heparin use.
Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic vasculitis, and cases of AAV complicated with HIT are rare.
In addition, it mostly occurs in patients undergoing hemodialysis.
Case Presentation.
An 87-year-old woman presented with rapidly progressive renal failure and severe leg edema.
She was diagnosed with AAV and treated with glucocorticoid and heparin calcium to prevent deep vein thrombosis.
Eight days after the start of heparin calcium, her platelet count decreased and the anti-platelet factor 4-heparin complex antibody was strongly positive (>5.0 U/mL; the cutoff point of the anti-platelet factor 4-heparin complex antibody evaluated by the latex turbidity assay is 1.0 U/mL).
She was diagnosed with HIT and treated with argatroban.
Subsequently, her platelet counts increased gradually.
Conclusion.
We encountered a case of HIT that developed prior to the induction of hemodialysis in the clinical course of AAV.
When AAV clinical course presents thrombocytopenia, the possibility of HIT should be considered.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nonaka, Taketoshi& Harada, Makoto& Sumi, Masahiko& Ishii, Wataru& Ichikawa, Tohru& Kobayashi, Mamoru. 2019. A Case of Heparin-Induced Thrombocytopenia That Developed in the Therapeutic Course of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis. Case Reports in Rheumatology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1144201
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nonaka, Taketoshi…[et al.]. A Case of Heparin-Induced Thrombocytopenia That Developed in the Therapeutic Course of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis. Case Reports in Rheumatology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1144201
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nonaka, Taketoshi& Harada, Makoto& Sumi, Masahiko& Ishii, Wataru& Ichikawa, Tohru& Kobayashi, Mamoru. A Case of Heparin-Induced Thrombocytopenia That Developed in the Therapeutic Course of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis. Case Reports in Rheumatology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1144201
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1144201
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر