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Severely Disseminated Kaposi Sarcoma after ABO-Incompatible Kidney Transplantation Treated Successfully with Paclitaxel and Gemcitabine Combined with Hemodialysis
المؤلفون المشاركون
Junker, Niels
Krarup-Hansen, Anders
Bomholt, Tobias
Egfjord, Martin
Sørensen, Søren Schwartz
المصدر
Case Reports in Transplantation
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-11
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Kaposi Sarcoma (KS) is driven by human herpes virus 8 causing vascular proliferation which is induced by loss of immune function most often due to HIV or immunosuppressants.
KS occurs with increased incidence in kidney transplant recipients, but rarely is disseminated.
We report a 64-year-old male who developed severely disseminated KS 5 months after ABO-incompatible kidney-transplantation.
No guidelines for chemotherapy exist in this case and reduced kidney function and impaired immune system complicates the use of systemic chemotherapy in kidney transplant recipients.
A combination of paclitaxel and gemcitabine followed by two days of hemodialysis treatment was chosen since paclitaxel can be given in full dose independently of kidney function and gemcitabine is metabolised to 2′,2′-difluorodeoxyuridine which is found to be highly dialysable.
The present treatment was well tolerated by the patient with one episode of leukopenia and elevated alanine transaminase during treatment which resolved.
There were no serious adverse events and the patient obtained a complete remission verified by Positron Emission Tomography CT after ending chemotherapy and at one-year follow up.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bomholt, Tobias& Krarup-Hansen, Anders& Egfjord, Martin& Sørensen, Søren Schwartz& Junker, Niels. 2019. Severely Disseminated Kaposi Sarcoma after ABO-Incompatible Kidney Transplantation Treated Successfully with Paclitaxel and Gemcitabine Combined with Hemodialysis. Case Reports in Transplantation،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1145259
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bomholt, Tobias…[et al.]. Severely Disseminated Kaposi Sarcoma after ABO-Incompatible Kidney Transplantation Treated Successfully with Paclitaxel and Gemcitabine Combined with Hemodialysis. Case Reports in Transplantation No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1145259
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bomholt, Tobias& Krarup-Hansen, Anders& Egfjord, Martin& Sørensen, Søren Schwartz& Junker, Niels. Severely Disseminated Kaposi Sarcoma after ABO-Incompatible Kidney Transplantation Treated Successfully with Paclitaxel and Gemcitabine Combined with Hemodialysis. Case Reports in Transplantation. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1145259
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1145259
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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