FOXE1 Mutation Screening in a Case with Cleft Lip, Hypothyroidism, and Thyroid Carcinoma: A New Syndrome?

المؤلفون المشاركون

Jiménez-Rosales, Angélica
Pérez-Amado, Carlos Jhovani
Jiménez-Morales, Silvia
Mendieta Zeron, Hugo

المصدر

Case Reports in Genetics

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-08-27

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الأحياء

الملخص EN

A 26-year-old woman is referred to the Internal Medicine consultation due to increases in laboratory studies associated with Papillary Thyroid Carcinoma (PTC) that was confirmed by histopathological studies.

Her clinical history revealed that, at 3 months of age, she was successfully treated with surgery for cleft lip (CL) and at the age of 24 years was diagnosed with hypothyroidism.

Single nucleotide polymorphisms (SNPs) in FOXE1 and its promoter regions have been associated with various etiologies related to the thyroid, including orofacial clefting, specially cleft palate (CP) and CL, hypothyroidism (HT), and thyroid cancer.

The association of CL, HT, and PTC might be component of a new syndrome; however FOXE1 coding region, which has been involved with these entities, has not exhibited mutations or SNPs.

Further study of other genes may help in better characterization of the possible syndrome.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Mendieta Zeron, Hugo& Jiménez-Rosales, Angélica& Pérez-Amado, Carlos Jhovani& Jiménez-Morales, Silvia. 2017. FOXE1 Mutation Screening in a Case with Cleft Lip, Hypothyroidism, and Thyroid Carcinoma: A New Syndrome?. Case Reports in Genetics،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1145366

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Mendieta Zeron, Hugo…[et al.]. FOXE1 Mutation Screening in a Case with Cleft Lip, Hypothyroidism, and Thyroid Carcinoma: A New Syndrome?. Case Reports in Genetics No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1145366

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Mendieta Zeron, Hugo& Jiménez-Rosales, Angélica& Pérez-Amado, Carlos Jhovani& Jiménez-Morales, Silvia. FOXE1 Mutation Screening in a Case with Cleft Lip, Hypothyroidism, and Thyroid Carcinoma: A New Syndrome?. Case Reports in Genetics. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1145366

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1145366