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Endocan, a Risk Factor for Developing Acute Respiratory Distress Syndrome among Severe Pneumonia Patients
المؤلفون المشاركون
Ying, Jun
Zhou, Danfei
Gu, Tongjie
Huang, Jianda
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-01
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Severe pneumonia (SP) has been widely accepted as a major cause for acute respiratory distress syndrome (ARDS), and the development of ARDS is significantly associated with increased mortality.
This study aimed to identify potential predictors for ARDS development in patients with SP.
Methods.
Eligible SP patients at admission from January 2013 to June 2017 were prospectively enrolled, and ARDS development within hospital stay was identified.
Risk factors for ARDS development in SP patients were analyzed by univariate and multivariate logistic regression analysis.
The receiver operating characteristic (ROC) curve analysis with the area under the curve (AUC) was performed for the predictive value of endocan for ARDS development.
Results.
A total of 145 SP patients were eventually enrolled into the final analysis, of which 37 developed ARDS during the hospital stay.
Our final multivariate logistic regression analysis suggested plasma endocan expression as the only independent risk factor for ARDS development in SP patients (OR: 1.57, 95% CI: 1.14–2.25, P=0.021).
ROC curve analysis of plasma endocan resulted in an AUC of 0.754, 95% CI of 0.642–0.866, a cutoff value of 11.6 ng/mL, a sensitivity of 78.7%, and a specificity of 70.3%, respectively (P<0.01).
Conclusions.
Endocan expression at ICU admission is a reliable predictive factor in predicting ARDS in patients with SP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ying, Jun& Zhou, Danfei& Gu, Tongjie& Huang, Jianda. 2019. Endocan, a Risk Factor for Developing Acute Respiratory Distress Syndrome among Severe Pneumonia Patients. Canadian Respiratory Journal،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1145690
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ying, Jun…[et al.]. Endocan, a Risk Factor for Developing Acute Respiratory Distress Syndrome among Severe Pneumonia Patients. Canadian Respiratory Journal No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1145690
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ying, Jun& Zhou, Danfei& Gu, Tongjie& Huang, Jianda. Endocan, a Risk Factor for Developing Acute Respiratory Distress Syndrome among Severe Pneumonia Patients. Canadian Respiratory Journal. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1145690
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1145690
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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