Sertoli-Leydig Cell Tumour and DICER1 Mutation: A Case Report and Review of the Literature

الملخص EN

Sertoli-Leydig cell tumours of the ovary (SLCT) are rare tumours predominantly caused by mutations in the DICER1 gene.

We present a patient with a unilateral SLCT who had an underlying germline DICER1 gene mutation.

We discuss the underlying pathology, risks, and screening opportunities available to those with a mutation in this gene as SLCT is only one of a multitude of other tumours encompassing DICER1 syndrome.

The condition is inherited in an autosomal dominant fashion.

As such, genetic counselling is a key component of the management of women with SLCT.