Sertoli-Leydig Cell Tumour and DICER1 Mutation: A Case Report and Review of the Literature
Joint Authors
Wormald, B.
Elorbany, S.
Hanson, H.
Williams, J. W.
Heenan, S.
Barton, D. P. J.
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-25
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Sertoli-Leydig cell tumours of the ovary (SLCT) are rare tumours predominantly caused by mutations in the DICER1 gene.
We present a patient with a unilateral SLCT who had an underlying germline DICER1 gene mutation.
We discuss the underlying pathology, risks, and screening opportunities available to those with a mutation in this gene as SLCT is only one of a multitude of other tumours encompassing DICER1 syndrome.
The condition is inherited in an autosomal dominant fashion.
As such, genetic counselling is a key component of the management of women with SLCT.
American Psychological Association (APA)
Wormald, B.& Elorbany, S.& Hanson, H.& Williams, J. W.& Heenan, S.& Barton, D. P. J.. 2018. Sertoli-Leydig Cell Tumour and DICER1 Mutation: A Case Report and Review of the Literature. Case Reports in Obstetrics and Gynecology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145933
Modern Language Association (MLA)
Wormald, B.…[et al.]. Sertoli-Leydig Cell Tumour and DICER1 Mutation: A Case Report and Review of the Literature. Case Reports in Obstetrics and Gynecology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1145933
American Medical Association (AMA)
Wormald, B.& Elorbany, S.& Hanson, H.& Williams, J. W.& Heenan, S.& Barton, D. P. J.. Sertoli-Leydig Cell Tumour and DICER1 Mutation: A Case Report and Review of the Literature. Case Reports in Obstetrics and Gynecology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145933
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145933
