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Bone Marrow-Liver-Spleen Type of Large B-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Rare Aggressive Extranodal Lymphoma
المؤلفون المشاركون
Chapman-Fredericks, Jennifer
Lyapichev, K.
Vega, Francisco
Iakymenko, Oleksii
Teomete, Uygar
Sanchez, Sandra Patricia
Ikpatt, Offiong Francis
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-01
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Recently, an unusual subtype of large B-cell lymphoma (LBCL) with distinctive clinicopathologic features has been recognized; it is characterized by involvement of bone marrow with or without liver and/or spleen, but no lymph node or other extranodal sites, usually associated with fever, anemia, and hemophagocytic lymphohistiocytosis (HLH).
Because of this distinctive clinical presentation, it has been designated “bone marrow-liver-spleen” (BLS) type of LBCL.
To date there is only one series of 11 cases of BLS type of LBCL with detailed clinical, pathologic, and cytogenetic data.
Herein, we describe a case of BLS type LBCL presenting with associated HLH in a 73-year-old female.
The bone marrow core biopsy showed cytologically atypical large lymphoma cells present in a scattered interstitial distribution and hemophagocytosis and infrequent large lymphoma cells were seen in the bone marrow aspirate smears.
Circulating lymphoma cells were not seen in the peripheral blood smears.
The patient underwent treatment with chemotherapy (R-CHOP) but unfortunately passed away 2 months after initial presentation.
BLS type of LBCL is a very rare and clinically aggressive lymphoma whose identification may be delayed by clinicians and hematopathologists due to its unusual clinical presentation and pathologic features.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lyapichev, K.& Chapman-Fredericks, Jennifer& Iakymenko, Oleksii& Ikpatt, Offiong Francis& Teomete, Uygar& Sanchez, Sandra Patricia…[et al.]. 2017. Bone Marrow-Liver-Spleen Type of Large B-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Rare Aggressive Extranodal Lymphoma. Case Reports in Hematology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1146033
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lyapichev, K.…[et al.]. Bone Marrow-Liver-Spleen Type of Large B-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Rare Aggressive Extranodal Lymphoma. Case Reports in Hematology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1146033
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lyapichev, K.& Chapman-Fredericks, Jennifer& Iakymenko, Oleksii& Ikpatt, Offiong Francis& Teomete, Uygar& Sanchez, Sandra Patricia…[et al.]. Bone Marrow-Liver-Spleen Type of Large B-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Rare Aggressive Extranodal Lymphoma. Case Reports in Hematology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1146033
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1146033
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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