Necrotizing Liver GranulomaAbscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granulomatous Disease Genotypes

المؤلفون المشاركون

Aksu, Guzide
Akarcan, Sanem
Bozkaya, Halil
Ayik, Mehmet Fatih
Ozdemir Sahan, Yasemin
Kilinc, Mehmet Arda
Dokumcu, Zafer
Eraslan, Cenk
Divarci, Emre
Alper, Hudaver
Kutukculer, Necil
Karaca, Neslihan

المصدر

Case Reports in Immunology

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-01-10

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

الأحياء

الملخص EN

Chronic granulomatous disease (CGD) is a primary immune deficiency causing predisposition to infections with specific microorganisms, Aspergillus species and Staphylococcus aureus being the most common ones.

A 16-year-old boy with a mutation in CYBB gene coding gp91phox protein (X-linked disease) developed a liver abscess due to Staphylococcus aureus.

In addition to medical therapy, surgical treatment was necessary for the management of the disease.

A 30-month-old girl with an autosomal recessive form of chronic granulomatous disease (CYBA gene mutation affecting p22phox protein) had invasive aspergillosis causing pericarditis, pulmonary abscess, and central nervous system involvement.

The devastating course of disease regardless of the mutation emphasizes the importance of early diagnosis and intervention of hematopoietic stem cell transplantation as soon as possible in children with CGD.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Akarcan, Sanem& Karaca, Neslihan& Aksu, Guzide& Bozkaya, Halil& Ayik, Mehmet Fatih& Ozdemir Sahan, Yasemin…[et al.]. 2017. Necrotizing Liver GranulomaAbscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granulomatous Disease Genotypes. Case Reports in Immunology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1146156

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Akarcan, Sanem…[et al.]. Necrotizing Liver GranulomaAbscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granulomatous Disease Genotypes. Case Reports in Immunology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1146156

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Akarcan, Sanem& Karaca, Neslihan& Aksu, Guzide& Bozkaya, Halil& Ayik, Mehmet Fatih& Ozdemir Sahan, Yasemin…[et al.]. Necrotizing Liver GranulomaAbscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granulomatous Disease Genotypes. Case Reports in Immunology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1146156

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1146156