Necrotizing Liver GranulomaAbscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granulomatous Disease Genotypes
Joint Authors
Aksu, Guzide
Akarcan, Sanem
Bozkaya, Halil
Ayik, Mehmet Fatih
Ozdemir Sahan, Yasemin
Kilinc, Mehmet Arda
Dokumcu, Zafer
Eraslan, Cenk
Divarci, Emre
Alper, Hudaver
Kutukculer, Necil
Karaca, Neslihan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Chronic granulomatous disease (CGD) is a primary immune deficiency causing predisposition to infections with specific microorganisms, Aspergillus species and Staphylococcus aureus being the most common ones.
A 16-year-old boy with a mutation in CYBB gene coding gp91phox protein (X-linked disease) developed a liver abscess due to Staphylococcus aureus.
In addition to medical therapy, surgical treatment was necessary for the management of the disease.
A 30-month-old girl with an autosomal recessive form of chronic granulomatous disease (CYBA gene mutation affecting p22phox protein) had invasive aspergillosis causing pericarditis, pulmonary abscess, and central nervous system involvement.
The devastating course of disease regardless of the mutation emphasizes the importance of early diagnosis and intervention of hematopoietic stem cell transplantation as soon as possible in children with CGD.
American Psychological Association (APA)
Akarcan, Sanem& Karaca, Neslihan& Aksu, Guzide& Bozkaya, Halil& Ayik, Mehmet Fatih& Ozdemir Sahan, Yasemin…[et al.]. 2017. Necrotizing Liver GranulomaAbscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granulomatous Disease Genotypes. Case Reports in Immunology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1146156
Modern Language Association (MLA)
Akarcan, Sanem…[et al.]. Necrotizing Liver GranulomaAbscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granulomatous Disease Genotypes. Case Reports in Immunology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1146156
American Medical Association (AMA)
Akarcan, Sanem& Karaca, Neslihan& Aksu, Guzide& Bozkaya, Halil& Ayik, Mehmet Fatih& Ozdemir Sahan, Yasemin…[et al.]. Necrotizing Liver GranulomaAbscess and Constrictive Aspergillosis Pericarditis with Central Nervous System Involvement: Different Remarkable Phenotypes in Different Chronic Granulomatous Disease Genotypes. Case Reports in Immunology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1146156
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146156