Life-Threatening Intrapulmonary Hemorrhage due to Vancomycin-Induced Thrombocytopenia: A Case Report
المؤلفون المشاركون
Abdalhadi, Haneen
Fahmawi, Yazan
Das, Abhijin
Fouty, Brian
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-30
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Thrombocytopenia is a rare and sometimes life-threatening complication of Vancomycin.
A 52-year-old male patient with acute kidney injury was treated with Vancomycin for ventilator-associated pneumonia.
Three days later, his platelets decreased from 172×109/L to 3×109/L over a 36-hour period.
The patient developed significant intrapulmonary bleeding leading to profound hypoxemia.
Workup was negative for thrombotic thrombocytopenic purpura, disseminated intravascular coagulopathy, atypical hemolytic uremic syndrome, heparin-induced thrombocytopenia, and autoimmune diseases.
All recently started medications were discontinued, and the patient was started empirically on methylprednisolone and intravenous immunoglobulin.
The patient’s platelets increased, and his airway bleeding stopped within 48 hours; his platelet count returned to normal by 18 days.
Vancomycin-dependent anti-platelet antibodies were identified in the patient’s serum by flow cytometry.
Thrombocytopenia is an underrecognized complication of Vancomycin that can lead to life-threating bleeding.
Stopping Vancomycin may be sufficient to reverse the thrombocytopenia in patients with normal renal function, but more aggressive measures such as steroids, IVIG, and dialysis may be required to stop bleeding and reverse thrombocytopenia in patients with underlying kidney injury who cannot effectively excrete Vancomycin.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abdalhadi, Haneen& Fahmawi, Yazan& Das, Abhijin& Fouty, Brian. 2020. Life-Threatening Intrapulmonary Hemorrhage due to Vancomycin-Induced Thrombocytopenia: A Case Report. Case Reports in Critical Care،Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1146354
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abdalhadi, Haneen…[et al.]. Life-Threatening Intrapulmonary Hemorrhage due to Vancomycin-Induced Thrombocytopenia: A Case Report. Case Reports in Critical Care No. 2020 (2020), pp.1-3.
https://search.emarefa.net/detail/BIM-1146354
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abdalhadi, Haneen& Fahmawi, Yazan& Das, Abhijin& Fouty, Brian. Life-Threatening Intrapulmonary Hemorrhage due to Vancomycin-Induced Thrombocytopenia: A Case Report. Case Reports in Critical Care. 2020. Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1146354
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1146354
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر