A Case of Spontaneously Improving Secondary Hemophagocytic Lymphohistiocytosis in an Adult Associated with T-Cell Histiocyte-Rich Large B-Cell Lymphoma
المؤلفون المشاركون
Burris, Ashley
Askin, Cyrus
Layman, Clifton
Haney, Brian
Hall, Jordan
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-22
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Secondary hemophagocytic lymphohistiocytosis (HLH) in adults is a rare, often fatal syndrome characterized by widespread immune dysregulation.
It is seen as a complication of infections, autoimmune diseases, and malignancies.
Among the malignancy-related causes, aggressive T-cell or NK-cell neoplasms are most notable, while B-cell lymphomas are less commonly implicated.
We present the case of a 32-year-old male transferred to our facility with concern for HLH.
During the first week of his hospitalization, his diagnosis was confirmed and the patient demonstrated spontaneous improvement in his symptoms prompting us to delay therapy while searching for a primary cause.
In the second week, the patient deteriorated, leading us to initiate steroid monotherapy in the absence of a cause for his HLH.
Meanwhile, pathology results from an excisional lymph node biopsy confirmed a diagnosis of T-cell/histiocyte-rich large B-cell lymphoma (TCHRLBCL).
Subsequently, we initiated therapy with dose-adjusted R-EPOCH.
The patient achieved a complete remission of both HLH and TCHRLBCL as well as a complete return to his prior functional status.
In our review of the literature, this represents only the second documented case of HLH associated with TCHRLBCL and the only documented case of an adult experiencing significant spontaneous recovery in this context.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Askin, Cyrus& Burris, Ashley& Layman, Clifton& Haney, Brian& Hall, Jordan. 2018. A Case of Spontaneously Improving Secondary Hemophagocytic Lymphohistiocytosis in an Adult Associated with T-Cell Histiocyte-Rich Large B-Cell Lymphoma. Case Reports in Oncological Medicine،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1146597
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Askin, Cyrus…[et al.]. A Case of Spontaneously Improving Secondary Hemophagocytic Lymphohistiocytosis in an Adult Associated with T-Cell Histiocyte-Rich Large B-Cell Lymphoma. Case Reports in Oncological Medicine No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1146597
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Askin, Cyrus& Burris, Ashley& Layman, Clifton& Haney, Brian& Hall, Jordan. A Case of Spontaneously Improving Secondary Hemophagocytic Lymphohistiocytosis in an Adult Associated with T-Cell Histiocyte-Rich Large B-Cell Lymphoma. Case Reports in Oncological Medicine. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1146597
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1146597
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر