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Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma
المؤلفون المشاركون
Sasano, Hironobu
Oba, Kazuhito
Chiba, Yuko
Matsuda, Yoko
Kumakawa, Takeshi
Aoyama, Rie
Akahoshi, Miho
Hashimoto, Seiji
Tachibana, Aya
Toyoshima, Koichi
Kodera, Remi
Toyoshima, Kenji
Tamura, Yoshiaki
Nagata, Takashi
Yamazaki, Yuto
Araki, Atsushi
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
A 47-year-old woman with a history of diabetes mellitus (DM) and obesity was admitted to our hospital for glucose control.
She was detected to have hypertension (HT) and diagnosed with primary aldosteronism (PA) based on the high level of aldosterone to renin ratio and the results of the upright furosemide-loading test according to the criteria of the Japanese Society of Hypertension (JSH) guidelines.
Computed tomography revealed left renal tumor and adrenocortical adenoma.
She underwent left nephrectomy and adrenalectomy.
The pathological findings were clear-cell renal cell carcinoma (RCC) and nonfunctional adrenocortical adenoma.
Her nonneoplastic adrenal tissue histologically revealed CYP11B2-positive multiple adrenocortical micronodules (MNs) and concomitant paradoxical hyperplasia of the zona glomerulosa.
Therefore, MNs were thought to be responsible for PA in this patient.
After surgery, HT was improved, and the result of upright furosemide-loading test after 12 months of surgery did not fulfill the criteria of PA according to the JSH guidelines.
However, the adrenocorticotrophic hormone stimulation test was positive; considering the possibility of slight aldosterone overproduction from the right adrenal gland, the administration of spironolactone was started.
Herein, we report a rare case of RCC in conjunction with PA histologically associated with MNs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Oba, Kazuhito& Chiba, Yuko& Matsuda, Yoko& Kumakawa, Takeshi& Aoyama, Rie& Akahoshi, Miho…[et al.]. 2020. Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma. Case Reports in Endocrinology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1146999
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Oba, Kazuhito…[et al.]. Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma. Case Reports in Endocrinology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1146999
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Oba, Kazuhito& Chiba, Yuko& Matsuda, Yoko& Kumakawa, Takeshi& Aoyama, Rie& Akahoshi, Miho…[et al.]. Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma. Case Reports in Endocrinology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1146999
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1146999
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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