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Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer
المؤلفون المشاركون
Sakamoto, Kazuhiro
Takahashi, Rina
Sugimoto, Kiichi
Motegi, Shunsuke
Tsukamoto, Ryoichi
Ichikawa, Ryosuke
Okazawa, Yu
Aoki, Jun
Takahashi, Makoto
Kojima, Yutaka
Okuzawa, Atsushi
Tomiki, Yuichi
Matsuoka, Joe
Ishiyama, Shun
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-16
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
We examined serum anti-p53 antibodies (S-p53Ab) in colorectal cancer.
Specifically, we retrospectively investigated the use of S-p53Ab as a prognostic marker after surgery for colorectal cancer.
Materials and Methods.
The levels of S-p53Ab, carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) were measured in 160 colorectal cancer patients who underwent surgical treatment.
The rate of postoperative change (RPC) in the S-p53Ab titer was calculated as [subsequent antibody titer-lowest titer]/lowest titer.
Results.
A relationship between recurrence and RPC in the S-p53Ab titer was not observed in patients who tested negative for S-p53Ab preoperatively.
In addition, no patients, who tested negative for S-p53Ab preoperatively, tested positive for S-p53Ab at the follow-up after surgery.
Of the patients who tested positive for S-p53Ab preoperatively, those recurrences had a significantly higher RPC compared with those who did not (p<0.001).
Conclusions.
Although S-p53Ab is not a significant tumor marker in patients who test negative preoperatively, increases in the S-p53Ab titer should be continuously monitored and measured in patients who are positive for this antibody preoperatively, regardless of whether they later test negative.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Takahashi, Rina& Sakamoto, Kazuhiro& Sugimoto, Kiichi& Motegi, Shunsuke& Tsukamoto, Ryoichi& Ichikawa, Ryosuke…[et al.]. 2019. Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer. Disease Markers،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1147000
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Takahashi, Rina…[et al.]. Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer. Disease Markers No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1147000
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Takahashi, Rina& Sakamoto, Kazuhiro& Sugimoto, Kiichi& Motegi, Shunsuke& Tsukamoto, Ryoichi& Ichikawa, Ryosuke…[et al.]. Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1147000
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147000
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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