![](/images/graphics-bg.png)
Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients
المؤلفون المشاركون
Owczarek, Aleksander
Olszanecka-Glinianowicz, Magdalena
Wajda, Jarosław
Świat, Maciej
Chudek, Jerzy
Brzozowska, Aniceta
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-02
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Vitamin D (VD) deficiency is considered an independent risk factor for death due to cardiovascular events including ischemic stroke (IS).
We assessed the hypothesis that decreased levels of 25-hydroxyvitamin D (25-OH-D) are associated with increased risk of mortality in patients with IS.
Methods.
Serum 25-OH-D, intact parathyroid hormone (iPTH), and intact fibroblast growth factor 23 (iFGF23) levels were assessed in serum of 240 consecutive patients admitted within the 24 hours after the onset of IS.
Mortality data was obtained from the local registry office.
Results.
Only three subjects (1.3%) had an optimal 25-OH-D level (30-80 ng/mL), 25 (10.4%) had a mildly reduced (insufficient) level, 61 (25.4%) had moderate deficiency, and 151 (62.9%) had a severe VD deficiency.
20% subjects had secondary hyperparathyroidism.
The serum 25-OH-D level was significantly lower than that in 480 matched subjects (9.9±7.1 vs.
21.0±8.7 ng/mL).
Of all the patients, 79 (32.9%) died during follow-up observation (44.9 months).
The mortality rates (per year) were 4.81 and 1.89 in a group with and without severe VD deficiency, respectively (incidence rate ratio: 2.52; 95% CI: 1.44–4.68).
There was no effect of secondary hyperparathyroidism and iFGF23 levels on mortality rates.
Age, 25−OH−D<10 ng/mL, and functional status (modified Rankin scale) were significant factors increasing the risk of death in multivariable Cox proportional hazard regression test.
Conclusions.
Severe VD deficiency is an emerging, strong negative predictor for survival after IS, independent of age and functional status.
VD supplementation in IS survivals may be considered due to high prevalence of its deficiency.
However, it is uncertain whether it will improve their survival.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wajda, Jarosław& Świat, Maciej& Owczarek, Aleksander& Brzozowska, Aniceta& Olszanecka-Glinianowicz, Magdalena& Chudek, Jerzy. 2019. Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients. Disease Markers،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1147078
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wajda, Jarosław…[et al.]. Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients. Disease Markers No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1147078
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wajda, Jarosław& Świat, Maciej& Owczarek, Aleksander& Brzozowska, Aniceta& Olszanecka-Glinianowicz, Magdalena& Chudek, Jerzy. Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1147078
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147078
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)