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A Patient with Non-Hodgkin Lymphoma and Nonspecific Interstitial Pneumonia during Ibrutinib Therapy
المؤلفون المشاركون
Jungmann, Sven
Ludwig, Wolf-Dieter
Blum, Torsten-Gerriet
Großwendt, Claudia
Boch, Christian
Rehbock, Beate
Griff, Sergej
Schmittel, Alexander
Bauer, Torsten T.
Schönfeld, Nicolas
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-10
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
We present a 74-year-old male with nonspecific interstitial pneumonia (NSIP) during treatment with ibrutinib for mantle cell lymphoma.
Previously, the patient had received six cycles of bendamustine and rituximab and six cycles of R-CHOP, followed by rituximab maintenance therapy.
Respiratory tract complications of ibrutinib other than infectious pneumonia have not been mentioned in larger trials, but individual case reports hinted to a possible association with the development of pneumonitis.
In our patient, the onset of alveolitis that progressed towards NSIP together with the onset of ibrutinib treatment suggests causality.
One week after ibrutinib was discontinued, nasal symptoms resolved first.
A follow-up CT showed a reduction in the reticular hyperdensities and ground-glass opacities, suggestive of restitution of the lung disease.
To our knowledge, this is the first case showing a strong link between ibrutinib and interstitial lung disease, strengthening a previous report on subacute pneumonitis.
Our findings have clinical implications because pulmonary side effects were reversible at this early stage.
We, therefore, suggest close monitoring for respiratory side effects in patients receiving ibrutinib.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jungmann, Sven& Ludwig, Wolf-Dieter& Schönfeld, Nicolas& Blum, Torsten-Gerriet& Großwendt, Claudia& Boch, Christian…[et al.]. 2017. A Patient with Non-Hodgkin Lymphoma and Nonspecific Interstitial Pneumonia during Ibrutinib Therapy. Case Reports in Oncological Medicine،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147759
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jungmann, Sven…[et al.]. A Patient with Non-Hodgkin Lymphoma and Nonspecific Interstitial Pneumonia during Ibrutinib Therapy. Case Reports in Oncological Medicine No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1147759
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jungmann, Sven& Ludwig, Wolf-Dieter& Schönfeld, Nicolas& Blum, Torsten-Gerriet& Großwendt, Claudia& Boch, Christian…[et al.]. A Patient with Non-Hodgkin Lymphoma and Nonspecific Interstitial Pneumonia during Ibrutinib Therapy. Case Reports in Oncological Medicine. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147759
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147759
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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