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Lenalidomide-Associated Immune Thrombocytopenia: A Case Report and Review of the Literature
المؤلفون المشاركون
Forehand III, William
Ajebo, Germame
Toscano, Michael
Jillella, Anand
Dainer, Paul
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-12
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Lenalidomide is indicated in the front-line management of multiple myeloma.
More recently, it has been introduced for use in treating other hematologic malignancies.
Although the drug is known to cause myelosuppression, there have been rare reports of lenalidomide-associated immune thrombocytopenia (ITP).
Here, we review the literature on lenalidomide-associated ITP and report upon a 59-year-old man who was administered lenalidomide due to concern of progressive multiple myeloma more than a year following his having undergone an autologous hematopoietic stem cell transplant.
His platelet count precipitously declined and lead to his hospitalization.
Despite our withholding of the drug, he did not respond to platelet transfusions or administration of corticosteroids.
He was successfully managed with intermittent immune globulin for several months before definitive treatment with splenectomy, which resulted in the complete resolution of his thrombocytopenia.
A literature search identified a total of six additional cases of lenalidomide-associated ITP.
Similarly, many of the reported cases were associated with persistent thrombocytopenia after discontinuation of the drug.
Furthermore, these patients were generally managed successfully with standard ITP therapies, such as corticosteroids or intravenous immune globulin.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Forehand III, William& Ajebo, Germame& Toscano, Michael& Jillella, Anand& Dainer, Paul. 2020. Lenalidomide-Associated Immune Thrombocytopenia: A Case Report and Review of the Literature. Case Reports in Hematology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147808
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Forehand III, William…[et al.]. Lenalidomide-Associated Immune Thrombocytopenia: A Case Report and Review of the Literature. Case Reports in Hematology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1147808
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Forehand III, William& Ajebo, Germame& Toscano, Michael& Jillella, Anand& Dainer, Paul. Lenalidomide-Associated Immune Thrombocytopenia: A Case Report and Review of the Literature. Case Reports in Hematology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147808
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147808
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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