Treatment of Recurrent Clostridium difficile Infection in an Immunocompromised Patient with Severe Neutropenia Not Responding to Standard Therapy
المؤلفون المشاركون
AlQahtani, Hajar
Baloch, Saeed
Tabb, Deanne
المصدر
Case Reports in Infectious Diseases
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-26
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
One of the most effective strategies in reducing the risk of Clostridium difficile infection (CDI) recurrence is fecal microbiota transplantation (FMT).
However, several adverse events have been reported post FMT, and data on the efficacy and safety of FMT in immunocompromised patients with hematological malignancies are rare.
This report presents FMT treatment for refractory CDI in a severely immunocompromised patient.
A 69-year-old female presented to the emergency department complaining of foul smelling, intractable, watery diarrhea and generalized abdominal pain.
She was recently diagnosed with high-risk myelodysplastic Syndrome (MDS) requiring daily blood transfusions and reported multiple CDI episodes in the past treated successfully with metronidazole and vancomycin as mono- or combotherapy.
During this admission, treatment with oral vancomycin (high dose) and intravenous metronidazole was unsuccessful, so FMT was administered.
The patient recovered well despite an absolute neutrophil count (ANC) < 0.25 × 109/L, and chemotherapy was initiated soon after.
FMT was successful and safe in this patient, with no relapse and adverse events seen in 8 weeks of follow-up via phone calls and office visits.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
AlQahtani, Hajar& Baloch, Saeed& Tabb, Deanne. 2020. Treatment of Recurrent Clostridium difficile Infection in an Immunocompromised Patient with Severe Neutropenia Not Responding to Standard Therapy. Case Reports in Infectious Diseases،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148131
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
AlQahtani, Hajar…[et al.]. Treatment of Recurrent Clostridium difficile Infection in an Immunocompromised Patient with Severe Neutropenia Not Responding to Standard Therapy. Case Reports in Infectious Diseases No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1148131
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
AlQahtani, Hajar& Baloch, Saeed& Tabb, Deanne. Treatment of Recurrent Clostridium difficile Infection in an Immunocompromised Patient with Severe Neutropenia Not Responding to Standard Therapy. Case Reports in Infectious Diseases. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148131
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148131
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر