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Antioxidant, Hypoglycemic, and Neurobehavioral Effects of a Leaf Extract of Avicennia marina on Autoimmune Diabetic Mice
المؤلفون المشاركون
Abdel-Maksoud, Mostafa A.
Ajarem, Jamaan S.
Alatar, Abdulrahman
Okla, Mohammad K.
Alamri, Saud A.
Hegazy, Ahmed K.
Al-Ghamdi, Abdullah A.
Faisal, Mohammad
Abdel-Salam, Eslam M.
Ali, Hayssam M.
Salem, Mohamed Z. M.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-21
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Diabetes mellitus (DM) is a metabolic disease that can affect the central nervous system and behavioral traits in animals.
Streptozotocin-induced diabetes is considered an autoimmune disease.
The aim of the current study was to determine whether supplementation with the alcoholic extract of Avicennia marina leaves could improve diabetes-associated pathological changes.
The animals were divided into four groups: a control group (A), an A.
marina receiving nondiabetic group (B), a diabetic group (C), and a DM group orally supplemented with A.
marina alcoholic leaf extract (D).
The DM group of animals receiving the alcoholic extract of A.
marina leaves had reduced blood glucose levels, improved blood picture, and organ functions.
This group also showed improvement in locomotory behavior.
The results of this study showed that supplementation with the alcoholic extract of A.
marina leaves reduced oxidative stress and blood sugar levels, protected the liver, and improved the neurobehavioral changes associated with diabetes in mice.
Introducing alcoholic leaf extract of A.
marina to diabetic mice decreased inflammatory cells aggregation, vacuolation, and hemorrhage.
Additionally, a positive effect of the alcoholic leaf extract on the histopathological changes was observed in the testicular tissue of treated mice.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Okla, Mohammad K.& Alamri, Saud A.& Alatar, Abdulrahman& Hegazy, Ahmed K.& Al-Ghamdi, Abdullah A.& Ajarem, Jamaan S.…[et al.]. 2019. Antioxidant, Hypoglycemic, and Neurobehavioral Effects of a Leaf Extract of Avicennia marina on Autoimmune Diabetic Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1148462
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Okla, Mohammad K.…[et al.]. Antioxidant, Hypoglycemic, and Neurobehavioral Effects of a Leaf Extract of Avicennia marina on Autoimmune Diabetic Mice. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1148462
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Okla, Mohammad K.& Alamri, Saud A.& Alatar, Abdulrahman& Hegazy, Ahmed K.& Al-Ghamdi, Abdullah A.& Ajarem, Jamaan S.…[et al.]. Antioxidant, Hypoglycemic, and Neurobehavioral Effects of a Leaf Extract of Avicennia marina on Autoimmune Diabetic Mice. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1148462
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148462
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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