Dynamic Analysis of Metabolic Response in Gastric Ulcer (GU) Rats with Electroacupuncture Treatment Using 1H NMR-Based Metabolomics
المؤلفون المشاركون
Shen, Jia-cheng
Lian, Lin-yu
Zhang, Yuan
He, Qi-da
Chen, Jiao-long
Zhang, Long-bin
Huang, Miao-sen
Liu, Mi
Qian, Lin-chao
Liu, Cai-chun
Yang, Zhongbao
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-22
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Gastric ulcer (GU), a common digestive disease, has a high incidence and seriously endangers health of human.
According to the previous studies, it has been proved that electroacupuncture at acupoints of stomach meridian had a good effect on GU.
However, there are few published studies on metabolic response in gastric ulcer (GU) rats with electroacupuncture treatment.
Herein, we observed the metabolic profiles in biological samples (stomach, liver, and kidney) of GU rats with electroacupuncture treatment by 1H NMR metabolomics combined with pathological examination.
The male SD rats were induced by intragastric administration of 70% ethanol after fasting for 24 hours and treated by electroacupuncture at Zusanli (ST36) and Liangmen (ST21) for 1 day, 4 days, or 7 days, respectively.
And the conventional histopathological examinations as well as metabolic pathways assays were also performed.
We found that GU rats were basically cured after electroacupuncture treatment for 4 days and had a complete recovery after electroacupuncture treatment for 7 days by being modulated comprehensive metabolic changes, involved in the function of neurotransmitters, energy metabolism, cells metabolism, antioxidation, tissue repairing, and other metabolic pathways.
These findings may be helpful to facilitate the mechanism elucidating of electroacupuncture treatment on GU.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shen, Jia-cheng& Lian, Lin-yu& Zhang, Yuan& He, Qi-da& Chen, Jiao-long& Zhang, Long-bin…[et al.]. 2019. Dynamic Analysis of Metabolic Response in Gastric Ulcer (GU) Rats with Electroacupuncture Treatment Using 1H NMR-Based Metabolomics. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1148473
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shen, Jia-cheng…[et al.]. Dynamic Analysis of Metabolic Response in Gastric Ulcer (GU) Rats with Electroacupuncture Treatment Using 1H NMR-Based Metabolomics. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1148473
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shen, Jia-cheng& Lian, Lin-yu& Zhang, Yuan& He, Qi-da& Chen, Jiao-long& Zhang, Long-bin…[et al.]. Dynamic Analysis of Metabolic Response in Gastric Ulcer (GU) Rats with Electroacupuncture Treatment Using 1H NMR-Based Metabolomics. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1148473
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148473
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر