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Salvia miltiorrhiza Bunge (Danshen) for Treatment and Prevention of Urolithiasis: A Drosophila Animal Study
المؤلفون المشاركون
Chen, Huey-Yi
Chen, Wen-Chi
Man, Kee-Ming
Chou, Tzu-Yang
Yang, You-Rong
Tsai, Ming-Yen
Chen, Yung-Hsiang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-20
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Traditional Chinese medicine (TCM) has been prescribed for the treatment of stone disease for thousands of years.
Salvia miltiorrhiza (Danshen) was previously shown to have potential for treatment of stone disease in animal and clinical studies.
In this study, we further studied the antiurolithiasis effect of Danshen in a fly model.
Wild-type male Drosophila melanogaster CS flies were used in this study, with 0.25% ethylene glycol (EG) as a lithogenic agent.
2% potassium citrate (K-citrate) was the positive control agent for prevention (all agents added at the start of experiment) and treatment (drugs added after 2-week addition of lithogenic agent) studies compared with 15, 30, and 60 μg/ml of Danshen extract.
In the prevention study, both 2% K-citrate and Danshen (30 and 60 μg/ml) significantly inhibited EG-induced calcium oxalate (CaOx) crystal formation.
In the treatment study, only 2% K-citrate and high-dose of Danshen (60 μg/ml) significantly inhibited EG-induced CaOx crystal formation.
Survival analysis for EG with Danshen was compared with that for EG with K-citrate.
The mean lifespan was significantly reduced by administration of EG, and the results in the Danshen group were similar to those in the control group.
In conclusion, Danshen revealed both preventive and treatment effects on CaOx crystal formation in a fly model.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Wen-Chi& Chou, Tzu-Yang& Chen, Huey-Yi& Yang, You-Rong& Man, Kee-Ming& Tsai, Ming-Yen…[et al.]. 2019. Salvia miltiorrhiza Bunge (Danshen) for Treatment and Prevention of Urolithiasis: A Drosophila Animal Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1148546
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Wen-Chi…[et al.]. Salvia miltiorrhiza Bunge (Danshen) for Treatment and Prevention of Urolithiasis: A Drosophila Animal Study. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1148546
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Wen-Chi& Chou, Tzu-Yang& Chen, Huey-Yi& Yang, You-Rong& Man, Kee-Ming& Tsai, Ming-Yen…[et al.]. Salvia miltiorrhiza Bunge (Danshen) for Treatment and Prevention of Urolithiasis: A Drosophila Animal Study. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1148546
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148546
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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