Corneal Perforation during Combination Chemotherapy including Cetuximab in a Patient with a History of Herpetic Keratitis
المؤلفون المشاركون
Kusaka, Shunji
Kodama-Takahashi, Aya
Aomatsu, Keiichi
Fukuda, Masahiko
Sugioka, Koji
Mishima, Hiroshi
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-08
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Purpose.
To report a case of corneal perforation, in a patient with a history of herpetic keratitis, during combination chemotherapy including cetuximab.
Case.
We report the case of a 71-year-old man who was diagnosed with a hypopharyngeal carcinoma and received radiation therapy combined with cetuximab, the epidermal growth factor receptor (EGFR) inhibitor monoclonal antibody.
He was referred to us because of ocular hyperemia and corneal perforation in his left eye.
In spite of conservative therapy, his corneal perforation was exacerbated, with iris incarceration into the wound site and exposure to the surface of the cornea.
He therefore discontinued treatment with the combination chemotherapy and underwent lamellar keratoplasty using a preserved donor cornea.
After treatment with cetuximab resumed, there was no recurrence of the corneal perforation.
Conclusion.
We have presented the first case of cetuximab-related corneal perforation in a patient who had a history of recurrent herpetic keratitis.
EGFR inhibitors, such as cetuximab, can induce corneal perforation in cases with a history of herpetic stromal keratitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aomatsu, Keiichi& Sugioka, Koji& Kodama-Takahashi, Aya& Fukuda, Masahiko& Mishima, Hiroshi& Kusaka, Shunji. 2020. Corneal Perforation during Combination Chemotherapy including Cetuximab in a Patient with a History of Herpetic Keratitis. Case Reports in Oncological Medicine،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1149439
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aomatsu, Keiichi…[et al.]. Corneal Perforation during Combination Chemotherapy including Cetuximab in a Patient with a History of Herpetic Keratitis. Case Reports in Oncological Medicine No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1149439
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aomatsu, Keiichi& Sugioka, Koji& Kodama-Takahashi, Aya& Fukuda, Masahiko& Mishima, Hiroshi& Kusaka, Shunji. Corneal Perforation during Combination Chemotherapy including Cetuximab in a Patient with a History of Herpetic Keratitis. Case Reports in Oncological Medicine. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1149439
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1149439
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر