Galactomannan in Bronchoalveolar Lavage Fluid for Diagnosis of Invasive Pulmonary Aspergillosis with Nonneutropenic Patients

المؤلفون المشاركون

Ma, Hongying
Zhuang, Qidong
Zhang, Yun
Chen, Lei
Wang, Li
Zheng, Lin
Deng, Zaichun
Chen, Zhongbo

المصدر

Canadian Respiratory Journal

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-11-13

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Background.

We evaluated the utility of galactomannan (GM) in bronchoalveolar lavage fluid (BALF) for the diagnosis of invasive pulmonary aspergillosis (IPA) in nonneutropenic patients.

Methods.

A total of 183 patients were included in the final analysis.

Bronchoscopies and the detection of GM in BALF were all performed on them.

Results.

Ten cases of IPA were diagnosed.

ROC data demonstrated that, for diagnosing IPA, an optimal cutoff value for GM in BALF of 0.76 yielded a sensitivity of 100.0% and a specificity of 76.2%.

Symptoms and radiological findings had no significant difference between proven or probable IPA group and non-IPA group.

In our case-control analysis, although nine patients with false-positive results received treatment with Piperacillin/tazobactam, there was no significant difference between case and control group.

Conclusions.

BALF GM detection is a valuable adjunctive diagnostic tool.

Our retrospective study suggests that the optimal value of GM detection in BALF is 0.76 in nonneutropenic patients.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Zhuang, Qidong& Ma, Hongying& Zhang, Yun& Chen, Lei& Wang, Li& Zheng, Lin…[et al.]. 2017. Galactomannan in Bronchoalveolar Lavage Fluid for Diagnosis of Invasive Pulmonary Aspergillosis with Nonneutropenic Patients. Canadian Respiratory Journal،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1150812

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Zhuang, Qidong…[et al.]. Galactomannan in Bronchoalveolar Lavage Fluid for Diagnosis of Invasive Pulmonary Aspergillosis with Nonneutropenic Patients. Canadian Respiratory Journal No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1150812

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Zhuang, Qidong& Ma, Hongying& Zhang, Yun& Chen, Lei& Wang, Li& Zheng, Lin…[et al.]. Galactomannan in Bronchoalveolar Lavage Fluid for Diagnosis of Invasive Pulmonary Aspergillosis with Nonneutropenic Patients. Canadian Respiratory Journal. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1150812

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1150812