Investigation of Safety Profile of Four Copaifera Species and of Kaurenoic Acid by SalmonellaMicrosome Test
المؤلفون المشاركون
Bastos, Jairo Kennup
Martins, C. H. G.
Resende, Flávia Aparecida
Ambrosio, Sergio R.
Damasceno, Jaqueline L.
Arnet, Yadira Fernández
Fortunato, Giovanna Capaldi
Girotto, Luiza
Marena, Gabriel Davi
Rocha, Beatriz Patti
Veneziani, Rodrigo Cássio Sola
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-10
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Trees of the Copaifera genus are native to the tropical regions of Latin America and Western Africa.
Copaifera sp is widely used as a popular medicine and it has various ethnopharmacological indications, including gonorrhea, bronchitis, asthma, skin ulcers, ulcers, sore throat, uterine infections, general inflammations, cancer, and leishmanioses.
Kaurenoic acid is a naturally occurring diterpene found in Copaifera and has been used as an anti-inflammatory, treatment of ulcer, leishmaniasis, and cancer.
Bearing in mind the fact that the Ames test is an excellent tool to assess the safety of extracts, oils, and phytochemicals isolated from medicinal plants, from it, we evaluate the mutagenic potential of four species, between oleoresins (C.
oblongifolia; C.
langsdorffii) and leaves extracts (C.
lucens; C.
multijuga), of the Copaifera genus and also of kaurenoic acid, which is one of its major compounds.
The results showed that the Copaifera spp.
and kaurenoic acid did not induce an increase in the number of revertant colonies, without mutagenic effect in experiments, in the all concentrations evaluated by Ames test.
The results obtained in our study support the safe use of the Copaifera genus medicinal plants selected and of kaurenoic acid.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Damasceno, Jaqueline L.& Arnet, Yadira Fernández& Fortunato, Giovanna Capaldi& Girotto, Luiza& Marena, Gabriel Davi& Rocha, Beatriz Patti…[et al.]. 2019. Investigation of Safety Profile of Four Copaifera Species and of Kaurenoic Acid by SalmonellaMicrosome Test. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1151032
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Damasceno, Jaqueline L.…[et al.]. Investigation of Safety Profile of Four Copaifera Species and of Kaurenoic Acid by SalmonellaMicrosome Test. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1151032
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Damasceno, Jaqueline L.& Arnet, Yadira Fernández& Fortunato, Giovanna Capaldi& Girotto, Luiza& Marena, Gabriel Davi& Rocha, Beatriz Patti…[et al.]. Investigation of Safety Profile of Four Copaifera Species and of Kaurenoic Acid by SalmonellaMicrosome Test. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1151032
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1151032
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر