Effect of Polysaccharides from Bletilla striata on the Healing of Dermal Wounds in Mice
المؤلفون المشاركون
Zhang, Chen
He, Yanan
Chen, Zhejie
Shi, Jinfeng
Qu, Yan
Zhang, Jinming
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-24
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Bletilla striata has been largely used in traditional folk medicine in China as a wound healing agent and to treat gastritis and several other health problems.
Some studies have shown that plant polysaccharides may have the ability to promote wound healing.
The aim of this work was to evaluate the wound healing activity of the polysaccharide extracted from Bletilla striata.
Firstly, a Bletilla striata polysaccharide was extracted by water extraction and alcohol precipitation and characterized by Fourier transform infrared spectroscopy.
The Bletilla striata polysaccharide was then tested for cell migration and proliferation using the mouse fibroblast cell line.
Then, the Bletilla striata hydrogel was fabricated for acute wound health care of the mouse full-thickness excision.
The results showed that the BSP enhanced the proliferation and migration of L929 cells.
The superior wound healing capacity of the BSP hydrogel was demonstrated that it significantly accelerated the wound healing process in vivo in full-thickness skin defect wounded models.
Compared to the saline group, the BSP hydrogel could accelerate wound healing and promote re-epithelialization and collagen deposition by means of TGF-β/Smad signal pathway activation.
Taken together, BSP hydrogel would be a useful pharmaceutic candidate for acute cutaneous wound health care.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Chen& He, Yanan& Chen, Zhejie& Shi, Jinfeng& Qu, Yan& Zhang, Jinming. 2019. Effect of Polysaccharides from Bletilla striata on the Healing of Dermal Wounds in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1151618
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Chen…[et al.]. Effect of Polysaccharides from Bletilla striata on the Healing of Dermal Wounds in Mice. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1151618
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Chen& He, Yanan& Chen, Zhejie& Shi, Jinfeng& Qu, Yan& Zhang, Jinming. Effect of Polysaccharides from Bletilla striata on the Healing of Dermal Wounds in Mice. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1151618
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1151618
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر