Effects of Moxibustion and Moxa Smoke on Behavior Changes and Energy Metabolism in APPPS1 Mice
المؤلفون المشاركون
Yan, Zhi-Yi
Ha, Lue
Yu, Mengyun
Rui, Zhang
Zhao, Baixiao
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-08-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the antiaging effects of moxibustion and moxa smoke on APP/PS1 mice and to illustrate the mechanism of moxibustion improving Alzheimer’s disease (AD).
Methods.
36 male APP/PS1 mice were randomly assigned into three groups (n = 12), including a model control group, a moxibustion group, and a moxa smoke group.
In addition, 12 C57BL/6 normal mice served as a normal (negative) control group.
Mice in the moxibustion group received moxibustion intervention using Guanyuan (RN4) acupoint.
Mice in the moxa smoke group received moxa smoke exposure with the same frequency as the moxibustion group.
Behavioral tests were implemented in the 9th week, 3 days after the completion of the intervention.
Tricarboxylic acid cycle and fatty acid metabolomics assessments of the mice were determined after behavioral tests.
Results.
In this study, relative to normal mice, we found that AD mice showed altered tricarboxylic and fatty acid metabolism and showed behavioral changes consistent with the onset of AD.
However, both the moxibustion and moxa smoke interventions were able to mitigate these effects to some degree in AD mice.
Conclusions.
The data suggest that tricarboxylic acid cycle and unsaturated fatty acid metabolomics changes may be a target of AD, and the beneficial effects of moxibustion on cognitive behaviors may be mediated by the energy metabolism system.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ha, Lue& Yu, Mengyun& Yan, Zhi-Yi& Rui, Zhang& Zhao, Baixiao. 2019. Effects of Moxibustion and Moxa Smoke on Behavior Changes and Energy Metabolism in APPPS1 Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1151708
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ha, Lue…[et al.]. Effects of Moxibustion and Moxa Smoke on Behavior Changes and Energy Metabolism in APPPS1 Mice. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1151708
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ha, Lue& Yu, Mengyun& Yan, Zhi-Yi& Rui, Zhang& Zhao, Baixiao. Effects of Moxibustion and Moxa Smoke on Behavior Changes and Energy Metabolism in APPPS1 Mice. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1151708
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1151708
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر