Detection of Viruses by Multiplex Real-Time Polymerase Chain Reaction in Bronchoalveolar Lavage Fluid of Patients with Nonresponding Community-Acquired Pneumonia
المؤلفون المشاركون
Zhang, Rong
Huang, Huaqiong
Wang, Shaobin
Zhou, Hongwei
Han, Yinling
Jin, Zhangchu
Ying, Yinghua
Lan, Fen
Hua, Wen
Shen, Huahao
Li, Wen
Yan, Fugui
Zhang, Hao
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-26
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Nonresponding pneumonia is responsible for the most mortality of community-acquired pneumonia (CAP).
However, thus far, it is not clear whether viral infection plays an important role in the etiology of nonresponding CAP and whether there is a significant difference in the clinical characteristics between viral and nonviral nonresponding CAP.
Methods.
From 2016 to 2019, nonresponding CAP patients were retrospectively enrolled in our study.
All patients received bronchoalveolar lavage (BAL) and virus detection in BAL fluid by multiplex real-time polymerase chain reaction (PCR), and clinical, laboratory, and radiographic data were collected.
Results.
A total of 43 patients were included.
The median age was 62 years, and 65.1% of patients were male.
Overall, 20 patients (46.5%) were identified with viral infection.
Of these viruses, influenza virus (n = 8) and adenovirus (n = 7) were more frequently detected, and others included herpes simplex virus, human enterovirus, cytomegalovirus, human coronavirus 229E, rhinovirus, and parainfluenza virus.
Compared with nonviral nonresponding CAP, only ground-glass opacity combined with consolidation was a more common imaging manifestation in viral nonresponding CAP.
However, no obvious differences were found in clinical and laboratory findings between the presence and the absence of viral infections.
Conclusions.
Viral infections were particularly frequent in adults with nonresponding CAP.
The ground-glass opacity combined with consolidation was a specific imaging manifestation for viral nonresponding CAP, while the clinical and laboratory data showed no obvious differences between viral and nonviral nonresponding CAP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Hao& Han, Yinling& Jin, Zhangchu& Ying, Yinghua& Lan, Fen& Huang, Huaqiong…[et al.]. 2020. Detection of Viruses by Multiplex Real-Time Polymerase Chain Reaction in Bronchoalveolar Lavage Fluid of Patients with Nonresponding Community-Acquired Pneumonia. Canadian Respiratory Journal،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1152228
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Hao…[et al.]. Detection of Viruses by Multiplex Real-Time Polymerase Chain Reaction in Bronchoalveolar Lavage Fluid of Patients with Nonresponding Community-Acquired Pneumonia. Canadian Respiratory Journal No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1152228
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Hao& Han, Yinling& Jin, Zhangchu& Ying, Yinghua& Lan, Fen& Huang, Huaqiong…[et al.]. Detection of Viruses by Multiplex Real-Time Polymerase Chain Reaction in Bronchoalveolar Lavage Fluid of Patients with Nonresponding Community-Acquired Pneumonia. Canadian Respiratory Journal. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1152228
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152228
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر