A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score
المؤلفون المشاركون
Zhang, Shu
Hua, Wei
Hu, Yiran
Niu, Hongxia
Gu, Min
Liu, Xi
Yang, Shengwen
Ding, Li-Gang
Wang, Jing
المصدر
Cardiology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-28
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objectives.
It is important to identify super-responders who can derive most benefits from cardiac resynchronization therapy (CRT).
We aimed to establish a scoring model that can be used for predicting super-response to CRT.
Methods.
We retrospectively reviewed 387 CRT patients.
Multivariate logistic regression analysis was performed to identify predictors for super-response (defined as an absolute increase in left ventricular ejection fraction of ≥15% at 6-month follow-up) and to create a score model.
Multivariate Cox proportional-hazard regression analysis was conducted to assess associations with the long-term endpoint (defined as cardiac death/heart transplant, heart failure (HF) hospitalization, or all-cause death) across the score categories at follow-up.
Results.
Among 387 patients, 109 (28.2%) met super-response.
In multivariable analysis, 5 independent predictors (QQ-LAE) were identified: prior no fragmented QRS (odds ratio (OR) = 3.10 (1.39, 6.94)), QRS duration ≥170 ms (OR = 2.37 (1.35, 4.12)), left bundle branch block (OR = 2.57 (1.04, 6.37)), left atrial diameter <45 mm (OR = 3.27 (1.81, 5.89)), and left ventricular end-diastolic dimension <75 mm (OR = 4.11 (1.99, 8.48)).
One point was attributed to each predictor, and three score categories were identified.
The proportion of super-response after 6-month CRT implantation in patients with scores 0–3, 4, and 5 was 14.6%, 40.3%, and 64.1%, respectively (P<0.001).
Patients with score 5 had an 88% reduction in the risk of cardiac death/heart transplant (P=0.042), a 71% reduction in the risk of HF hospitalization (P=0.048), and an 89% reduction in the risk of all-cause mortality (P=0.028) compared to patients with scores 0–3.
Conclusions.
The QQ-LAE score can be used for prediction of super-response to CRT and selection of most suitable patients in clinical practices.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Xi& Hu, Yiran& Hua, Wei& Yang, Shengwen& Gu, Min& Niu, Hongxia…[et al.]. 2020. A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1152421
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Xi…[et al.]. A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score. Cardiology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1152421
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Xi& Hu, Yiran& Hua, Wei& Yang, Shengwen& Gu, Min& Niu, Hongxia…[et al.]. A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1152421
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152421
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر