Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer

المؤلفون المشاركون

Wang, Fang-Ming
Zhang, Guiming
Sun, Lijiang
Zhang, Yan
Liu, Ya-Nan
Liu, Yong

المصدر

Disease Markers

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-10-09

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الأمراض

الملخص EN

Purpose.

To investigate the association between ABO blood types and clinicopathological characteristics in patients with prostate cancer (PC).

Methods.

A total of 237 pathologically diagnosed PC patients were enrolled.

All patients were classified as low–middle or high-risk group.

The correlation of ABO blood types with high-risk PC was determined by univariate and multivariate regression analysis.

Results.

Data indicated 144 (85.7%) patients were stratified as high risk in the non-O group, while 50 (72.5%) patients in the O group (p=0.025).

However, there was no significant difference regarding PSA, Gleason score, stage, or metastasis between O and non-O group (p>0.05).

Univariate logistic regression analyses revealed PSA, Gleason score, and blood type non-O were all correlated with high-risk PC (OR = 1.139, p<0.001; OR = 9.465, p<0.001; OR = 2.280, p=0.018, resp.).

In the stepwise multivariate regression analysis, the association between blood type non-O and high-risk PC remained significant (OR = 33.066, 95% CI 2.391–457.323, and p=0.009) after adjusting for confounding factors as well as PSA and Gleason score.

Conclusion.

The present study firstly demonstrated that non-O blood type was at higher risk of aggressive PC compared with O type, suggesting that PC patients with non-O blood type should receive more attention in clinical practice.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Wang, Fang-Ming& Zhang, Yan& Zhang, Guiming& Liu, Ya-Nan& Sun, Lijiang& Liu, Yong. 2017. Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer. Disease Markers،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1152588

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Wang, Fang-Ming…[et al.]. Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer. Disease Markers No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1152588

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Wang, Fang-Ming& Zhang, Yan& Zhang, Guiming& Liu, Ya-Nan& Sun, Lijiang& Liu, Yong. Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1152588

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1152588