Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer
Joint Authors
Wang, Fang-Ming
Zhang, Guiming
Sun, Lijiang
Zhang, Yan
Liu, Ya-Nan
Liu, Yong
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To investigate the association between ABO blood types and clinicopathological characteristics in patients with prostate cancer (PC).
Methods.
A total of 237 pathologically diagnosed PC patients were enrolled.
All patients were classified as low–middle or high-risk group.
The correlation of ABO blood types with high-risk PC was determined by univariate and multivariate regression analysis.
Results.
Data indicated 144 (85.7%) patients were stratified as high risk in the non-O group, while 50 (72.5%) patients in the O group (p=0.025).
However, there was no significant difference regarding PSA, Gleason score, stage, or metastasis between O and non-O group (p>0.05).
Univariate logistic regression analyses revealed PSA, Gleason score, and blood type non-O were all correlated with high-risk PC (OR = 1.139, p<0.001; OR = 9.465, p<0.001; OR = 2.280, p=0.018, resp.).
In the stepwise multivariate regression analysis, the association between blood type non-O and high-risk PC remained significant (OR = 33.066, 95% CI 2.391–457.323, and p=0.009) after adjusting for confounding factors as well as PSA and Gleason score.
Conclusion.
The present study firstly demonstrated that non-O blood type was at higher risk of aggressive PC compared with O type, suggesting that PC patients with non-O blood type should receive more attention in clinical practice.
American Psychological Association (APA)
Wang, Fang-Ming& Zhang, Yan& Zhang, Guiming& Liu, Ya-Nan& Sun, Lijiang& Liu, Yong. 2017. Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer. Disease Markers،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1152588
Modern Language Association (MLA)
Wang, Fang-Ming…[et al.]. Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer. Disease Markers No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1152588
American Medical Association (AMA)
Wang, Fang-Ming& Zhang, Yan& Zhang, Guiming& Liu, Ya-Nan& Sun, Lijiang& Liu, Yong. Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1152588
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1152588