An Exploration of Traditional Chinese Medicinal Plants with Anti-Inflammatory Activities
المؤلفون المشاركون
Fan, Chao
Jin, Hui-zi
Wu, Lehao
Zhang, Yu
Ye, Richard D.
Zhang, Yan
Zhang, Weidong
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-04-04
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
In a continuing effort to discover more anti-inflammatory medicinal plants in China, the anti-inflammatory activities of 101 extracts from different parts of 84 traditional medicinal plants were evaluated by a panel of in vitro and in vivo assays.
Nuclear factor-kappa B (NF-κB) inhibitory effects were determined by luciferase assay in stably transfected Hela cells.
Cytotoxic activities were assessed using the MTT assay.
Inhibitory effects on LPS-induced nitric oxide production and proinflammatory mediators were assessed by Griess reaction and Real-Time PCR analysis, respectively.
In vivo anti-inflammatory activities were examined by xylene-induced mice ear edema model.
In total, 22 extracts showed promising NF-κB inhibitory effects whereas 9 of them did not affect the cell viability.
The 9 hit extracts were active in at least one of the subsequently performed in vitro pharmacological test systems.
The extract from Hemerocallis minor (root) was selected to perform the in vivo study because it demonstrated significant suppressive effects in all the in vitro assays.
Results showed that the extract of Hemerocallis minor (Root) was able to alleviate ear edema effectively in xylene-induced mice ear edema mode.
Collectively, our study provides evidence for the potential anti-inflammatory effects of the medicinal plants traditionally used in China.
Further phytochemical and pharmacological studies remain to be clarified.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fan, Chao& Jin, Hui-zi& Wu, Lehao& Zhang, Yu& Ye, Richard D.& Zhang, Weidong…[et al.]. 2017. An Exploration of Traditional Chinese Medicinal Plants with Anti-Inflammatory Activities. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1152949
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fan, Chao…[et al.]. An Exploration of Traditional Chinese Medicinal Plants with Anti-Inflammatory Activities. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1152949
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fan, Chao& Jin, Hui-zi& Wu, Lehao& Zhang, Yu& Ye, Richard D.& Zhang, Weidong…[et al.]. An Exploration of Traditional Chinese Medicinal Plants with Anti-Inflammatory Activities. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1152949
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152949
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر