Study on the Clinical Safe and Effective Methods of Arsenic-Containing Compound-Qinghuang Powder in the Treatment of Myelodysplastic Syndrome
المؤلفون المشاركون
Xiaomei, Hu
Zhu, Qianzhe
Deng, Zhongyang
Zhu, Shirong
Zhao, Pan
Wang, Mingjing
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-16
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
To establish the clinical safe and effective methods of arsenic-containing compound-Qinghuang Powder (compound-QHP) in the treatment of myelodysplastic syndrome (MDS).
Methods.
200 patients with MDS were treated with compound-QHP (daily dose of 0.1 g realgar).
The blood arsenic concentrations (BACs) were detected by atomic fluorescence spectrophotometry (HF-AFS).
After treatment for 1 month, the patients were randomly divided into group A and group B when the BACs were less than 20 μg/L.
Daily dose of realgar was maintained in group A and it was increased to that when the BACs were more than 20 μg/L in group B.
The BAC and clinical efficacy and safety in two groups were compared at the end of the treatment with compound-QHP.
Results.
The average BAC of group B was significantly higher than that of group A (P<0.01).
The rates of hematology improvement and reduced transfusion were significantly higher in group B than in group A (P<0.05).
The HGB, ANC, and PLT significantly increased in group B after treatment (P>0.05).
Conclusions.
Monitoring the BAC and adjusting the daily dose of realgar to increase the effective BAC and then improving efficacy without increasing the clinical toxicity are the clinical safe and effective methods in the treatment of MDS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhu, Qianzhe& Deng, Zhongyang& Zhu, Shirong& Zhao, Pan& Wang, Mingjing& Xiaomei, Hu. 2017. Study on the Clinical Safe and Effective Methods of Arsenic-Containing Compound-Qinghuang Powder in the Treatment of Myelodysplastic Syndrome. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1153208
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhu, Qianzhe…[et al.]. Study on the Clinical Safe and Effective Methods of Arsenic-Containing Compound-Qinghuang Powder in the Treatment of Myelodysplastic Syndrome. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1153208
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhu, Qianzhe& Deng, Zhongyang& Zhu, Shirong& Zhao, Pan& Wang, Mingjing& Xiaomei, Hu. Study on the Clinical Safe and Effective Methods of Arsenic-Containing Compound-Qinghuang Powder in the Treatment of Myelodysplastic Syndrome. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1153208
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153208
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر