![](/images/graphics-bg.png)
Effects of the Aqueous Extract from Tabebuia roseoalba and Phenolic Acids on Hyperuricemia and Inflammation
المؤلفون المشاركون
Ferraz-Filha, Zilma Schimith
Ferrari, Fernanda Cristina
Araújo, Marcela Carolina de Paula Michel
Bernardes, Ana Catharina Fernandes P. F.
Saúde-Guimarães, Dênia Antunes
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Tabebuia species (Bignoniaceae) have long been used in folk medicine as anti-inflammatory, antirheumatic, antimicrobial, and antitumor.
The aim of this study was to investigate if aqueous extract from the leaves (AEL) of Tabebuia roseoalba (Ridl.) Sandwith, Bignoniaceae, and its constituents could be useful to decrease serum uric acid levels and restrain the gout inflammatory process.
HPLC analysis identified caffeic acid and chlorogenic acid in AEL.
Antihyperuricemic effects and inhibition of liver XOD (xanthine oxidoreductase) by AEL and identified compounds were evaluated in hyperuricemic mice.
Anti-inflammatory activity was evaluated on MSU (monosodium urate) crystal-induced paw edema.
In addition, AEL antioxidant activity in vitro was evaluated.
AEL, caffeic, and chlorogenic acids were able to reduce serum uric acid levels in hyperuricemic mice probably through inhibition of liver xanthine oxidase activity and significantly decreased the paw edema induced by MSU crystals.
AEL showed significant antioxidant activity in all evaluated assays.
The results show that the AEL of Tabebuia roseoalba can be a promising agent for treatment for gout and inflammatory diseases.
We suggest that caffeic and chlorogenic acids may be responsible for the activities demonstrated by the species.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ferraz-Filha, Zilma Schimith& Ferrari, Fernanda Cristina& Araújo, Marcela Carolina de Paula Michel& Bernardes, Ana Catharina Fernandes P. F.& Saúde-Guimarães, Dênia Antunes. 2017. Effects of the Aqueous Extract from Tabebuia roseoalba and Phenolic Acids on Hyperuricemia and Inflammation. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153316
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ferraz-Filha, Zilma Schimith…[et al.]. Effects of the Aqueous Extract from Tabebuia roseoalba and Phenolic Acids on Hyperuricemia and Inflammation. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1153316
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ferraz-Filha, Zilma Schimith& Ferrari, Fernanda Cristina& Araújo, Marcela Carolina de Paula Michel& Bernardes, Ana Catharina Fernandes P. F.& Saúde-Guimarães, Dênia Antunes. Effects of the Aqueous Extract from Tabebuia roseoalba and Phenolic Acids on Hyperuricemia and Inflammation. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153316
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153316
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)