Anti-Inflammatory Activity of Babassu Oil and Development of a Microemulsion System for Topical Delivery
المؤلفون المشاركون
Silva, Márcia Vanusa da
Mattos, Alessandra B.
Santos, Simone Maria dos
Reis, Mysrayn Y. F. A.
Silva, Danielle R.
Navarro, Daniela M. A. Ferraz
Santos, Geanne K. N.
Hallwass, Fernando
Bianchi, Otávio
Melo, Janaína V.
Machado, Giovanna
Saraiva, Karina L. A.
Correia, Maria Tereza dos Santos
da Silva, Alexandre Gomes
Ximenes, Rafael Matos
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-21
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Babassu oil extraction is the main income source in nut breakers communities in northeast of Brazil.
Among these communities, babassu oil is used for cooking but also medically to treat skin wounds and inflammation, and vulvovaginitis.
This study aimed to evaluate the anti-inflammatory activity of babassu oil and develop a microemulsion system with babassu oil for topical delivery.
Topical anti-inflammatory activity was evaluated in mice ear edema using PMA, arachidonic acid, ethyl phenylpropiolate, phenol, and capsaicin as phlogistic agents.
A microemulsion system was successfully developed using a Span® 80/Kolliphor® EL ratio of 6 : 4 as the surfactant system (S), propylene glycol and water (3 : 1) as the aqueous phase (A), and babassu oil as the oil phase (O), and analyzed through conductivity, SAXS, DSC, TEM, and rheological assays.
Babassu oil and lauric acid showed anti-inflammatory activity in mice ear edema, through inhibition of eicosanoid pathway and bioactive amines.
The developed formulation (39% A, 12.2% O, and 48.8% S) was classified as a bicontinuous to o/w transition microemulsion that showed a Newtonian profile.
The topical anti-inflammatory activity of microemulsified babassu oil was markedly increased.
A new delivery system of babassu microemulsion droplet clusters was designed to enhance the therapeutic efficacy of vegetable oil.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Reis, Mysrayn Y. F. A.& Santos, Simone Maria dos& Silva, Danielle R.& Silva, Márcia Vanusa da& Correia, Maria Tereza dos Santos& Navarro, Daniela M. A. Ferraz…[et al.]. 2017. Anti-Inflammatory Activity of Babassu Oil and Development of a Microemulsion System for Topical Delivery. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1153548
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Reis, Mysrayn Y. F. A.…[et al.]. Anti-Inflammatory Activity of Babassu Oil and Development of a Microemulsion System for Topical Delivery. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1153548
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Reis, Mysrayn Y. F. A.& Santos, Simone Maria dos& Silva, Danielle R.& Silva, Márcia Vanusa da& Correia, Maria Tereza dos Santos& Navarro, Daniela M. A. Ferraz…[et al.]. Anti-Inflammatory Activity of Babassu Oil and Development of a Microemulsion System for Topical Delivery. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1153548
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153548
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر