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1H NMR-Based Metabonomic Study of Functional Dyspepsia in Stressed Rats Treated with Chinese Medicine Weikangning
المؤلفون المشاركون
Wei, Wei
Chen, Jiande DZ
Li, Zhongfeng
Zhu, Jia-Jie
Su, Xiao-Lan
Li, Yi-Jie
Wei, Ru-Han
Yang, Jian-Qin
Guo, Yu
Liu, Xinfeng
Song, Yilin
Zhang, Ping
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-18، 18ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-09-28
دولة النشر
مصر
عدد الصفحات
18
التخصصات الرئيسية
الملخص EN
1H NMR-based metabolic profiling combined with multivariate data analysis was used to explore the metabolic phenotype of functional dyspepsia (FD) in stressed rats and evaluate the intervention effects of the Chinese medicine Weikangning (WKN).
After a 7-day period of model establishment, a 14-day drug administration schedule was conducted in a WKN-treated group of rats, with the model and normal control groups serving as negative controls.
Based on 1H NMR spectra of urine and serum from rats, PCA, PLS-DA, and OPLS-DA were performed to identify changing metabolic profiles.
According to the key metabolites determined by OPLS-DA, alterations in energy metabolism, stress-related metabolism, and gut microbiota were found in FD model rats after stress stimulation, and these alterations were restored to normal after WKN administration.
This study may provide new insights into the relationship between FD and psychological stress and assist in research into the metabolic mechanisms involved in Chinese medicine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Guo, Yu& Li, Zhongfeng& Liu, Xinfeng& Su, Xiao-Lan& Li, Yi-Jie& Zhu, Jia-Jie…[et al.]. 2017. 1H NMR-Based Metabonomic Study of Functional Dyspepsia in Stressed Rats Treated with Chinese Medicine Weikangning. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-18.
https://search.emarefa.net/detail/BIM-1153644
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Guo, Yu…[et al.]. 1H NMR-Based Metabonomic Study of Functional Dyspepsia in Stressed Rats Treated with Chinese Medicine Weikangning. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-18.
https://search.emarefa.net/detail/BIM-1153644
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Guo, Yu& Li, Zhongfeng& Liu, Xinfeng& Su, Xiao-Lan& Li, Yi-Jie& Zhu, Jia-Jie…[et al.]. 1H NMR-Based Metabonomic Study of Functional Dyspepsia in Stressed Rats Treated with Chinese Medicine Weikangning. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-18.
https://search.emarefa.net/detail/BIM-1153644
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153644
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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