Meta-Analysis of the Use of 8-OHdG in Saliva as a Marker of Periodontal Disease
المؤلفون المشاركون
Almerich-Silla, Jose Manuel
Montiel-Company, Jose María
Paredes-Sánchez, Esther
Iranzo-Cortés, José Enrique
Almerich-Torres, Teresa
Bellot-Arcís, Carlos
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-02
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The objective was to collect the available evidence on oxidative stress marker measurements in periodontal patients, focusing specifically on 8-hydroxy-2′-deoxyguanosine (8-OHdG) as a salivary marker of periodontal disease, and to perform meta-analyses to calculate differences in concentration compared to healthy persons.
A systematic search in PubMed, Cochrane Library, Embase, and Scopus identified 81 articles.
Of these, 38 were duplicates.
After reading the abstracts of the remaining 43, 42 were selected for full-text assessment.
Finally, 17 articles were included in the qualitative synthesis.
Those excluded were of low quality, did not answer the research question, or did not meet the inclusion and exclusion criteria.
Of the 17 in the qualitative synthesis, 9 were included in the meta-analysis.
The 9 studies in the meta-analysis were combined in a random effects model.
Their heterogeneity was high (Q=3982.02, p<0.001, I2=99.8%).
The difference in mean 8-OHdG concentration in saliva between periodontal and healthy subjects was estimated at 2.11 ng/ml (95% CI 1.23–2.98).
The different saliva collection methods (stimulated/unstimulated) did not explain the heterogeneity.
The 8-OHdG levels in saliva of periodontal patients were almost double to those of healthy patients: 8-OHdG is clearly a powerful periodontal disease marker.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Paredes-Sánchez, Esther& Montiel-Company, Jose María& Iranzo-Cortés, José Enrique& Almerich-Torres, Teresa& Bellot-Arcís, Carlos& Almerich-Silla, Jose Manuel. 2018. Meta-Analysis of the Use of 8-OHdG in Saliva as a Marker of Periodontal Disease. Disease Markers،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1153671
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Paredes-Sánchez, Esther…[et al.]. Meta-Analysis of the Use of 8-OHdG in Saliva as a Marker of Periodontal Disease. Disease Markers No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1153671
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Paredes-Sánchez, Esther& Montiel-Company, Jose María& Iranzo-Cortés, José Enrique& Almerich-Torres, Teresa& Bellot-Arcís, Carlos& Almerich-Silla, Jose Manuel. Meta-Analysis of the Use of 8-OHdG in Saliva as a Marker of Periodontal Disease. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1153671
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153671
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر