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Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention
المؤلفون المشاركون
Ye, Ziliang
Lu, Haili
Li, Lang
Long, Manyun
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-17
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Whether serum uric acid (UA) is associated with all-cause mortality in patients with acute coronary syndrome (ACS) following percutaneous coronary intervention (PCI) remains unclear.
Methods.
We performed a retrospective cohort study of 2296 patients with ACS.
Curve-fitting and Cox proportional-hazard regression models with a hazard ratio (HR) and 95% confidence interval (CI) were used.
Results.
During a mean follow-up of 246.31 ± 49.16 days, 168 (7.32%) patients died from all causes.
Patients were divided into two groups [the high-UA group (n=566) and the low-UA group (n=1730)] based on the serum UA threshold value (5.6 mg/dl) identified through curve fitting.
Fifty-three (9.36%) patients died in the high-UA group, and 115 (6.65%) patients died in the low-UA group.
The difference between groups was statistically significant (P=0.031).
Univariate analysis showed that the risk of all-cause mortality in the high-UA group was significantly greater than that in the low-UA group (HR = 1.45, 95% CI: 1.03 to 2.04).
This difference persisted after adjustment for baseline characteristics, medical history, and medication history (HR = 1.42, 95% CI: 1.05 to 1.87).
Conclusions.
Our study demonstrated that elevated serum UA (>5.6 mg/dl) is associated with all-cause mortality in ASC patients after PCI.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ye, Ziliang& Lu, Haili& Long, Manyun& Li, Lang. 2018. Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention. Disease Markers،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153787
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ye, Ziliang…[et al.]. Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention. Disease Markers No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1153787
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ye, Ziliang& Lu, Haili& Long, Manyun& Li, Lang. Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153787
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153787
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