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Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention
Joint Authors
Ye, Ziliang
Lu, Haili
Li, Lang
Long, Manyun
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Whether serum uric acid (UA) is associated with all-cause mortality in patients with acute coronary syndrome (ACS) following percutaneous coronary intervention (PCI) remains unclear.
Methods.
We performed a retrospective cohort study of 2296 patients with ACS.
Curve-fitting and Cox proportional-hazard regression models with a hazard ratio (HR) and 95% confidence interval (CI) were used.
Results.
During a mean follow-up of 246.31 ± 49.16 days, 168 (7.32%) patients died from all causes.
Patients were divided into two groups [the high-UA group (n=566) and the low-UA group (n=1730)] based on the serum UA threshold value (5.6 mg/dl) identified through curve fitting.
Fifty-three (9.36%) patients died in the high-UA group, and 115 (6.65%) patients died in the low-UA group.
The difference between groups was statistically significant (P=0.031).
Univariate analysis showed that the risk of all-cause mortality in the high-UA group was significantly greater than that in the low-UA group (HR = 1.45, 95% CI: 1.03 to 2.04).
This difference persisted after adjustment for baseline characteristics, medical history, and medication history (HR = 1.42, 95% CI: 1.05 to 1.87).
Conclusions.
Our study demonstrated that elevated serum UA (>5.6 mg/dl) is associated with all-cause mortality in ASC patients after PCI.
American Psychological Association (APA)
Ye, Ziliang& Lu, Haili& Long, Manyun& Li, Lang. 2018. Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention. Disease Markers،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153787
Modern Language Association (MLA)
Ye, Ziliang…[et al.]. Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention. Disease Markers No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1153787
American Medical Association (AMA)
Ye, Ziliang& Lu, Haili& Long, Manyun& Li, Lang. Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153787
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153787