![](/images/graphics-bg.png)
Nyctanthes arbor-tristis Ameliorated FCA-Induced Experimental Arthritis: A Comparative Study among Different Extracts
المؤلفون المشاركون
Uroos, Maliha
Abbas, Zaigham
Sattar, Shumaila
Umer, Nigarish
Shabbir, Arham
Shafiq-ur-Rehman, Arham
Sharif, Ahsan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-06
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Nyctanthes arbor-tristis (NAT) is commonly used traditionally for the treatment of rheumatism and inflammatory diseases.
Current study evaluates the antiarthritic potential of NAT using Freund’s adjuvant-induced arthritic rat model.
Treatments with methanolic, ethyl acetate, and n-hexane extracts were continued for consecutive 20 days.
Macroscopic arthritic scoring and water displacement plethysmometry were used to evaluate arthritic development.
Hematological and biochemical parameters were investigated and ankle joints were processed for histopathological evaluation.
Qualitative phytochemical analysis and GC-MS analysis were conducted for identification of constituents.
NAT extracts suppressed arthritic scoring, paw edema, infiltration of inflammatory cells, pannus formation, and bone erosion.
The plant extracts ameliorated total leukocytes and platelet counts and nearly normalized red blood cells (RBC) counts and hemoglobin (Hb) content.
The extracts were found safe in terms of hepatotoxicity and nephrotoxicity as determined by aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, and urea levels.
Comparative analysis showed that ethyl acetate extract produced the highest inhibition of paw edema.
The major constituents found in ethyl acetate extract can be classified into three major classes, that is, terpenes, terpenoids, fatty acids, and iridoid glycosides.
Current study showed that Nyctanthes arbor-tristis ameliorated experimental rheumatoid arthritis and ethyl acetate extract possessed the highest inhibitory activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Uroos, Maliha& Abbas, Zaigham& Sattar, Shumaila& Umer, Nigarish& Shabbir, Arham& Shafiq-ur-Rehman, Arham…[et al.]. 2017. Nyctanthes arbor-tristis Ameliorated FCA-Induced Experimental Arthritis: A Comparative Study among Different Extracts. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1153819
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Uroos, Maliha…[et al.]. Nyctanthes arbor-tristis Ameliorated FCA-Induced Experimental Arthritis: A Comparative Study among Different Extracts. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1153819
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Uroos, Maliha& Abbas, Zaigham& Sattar, Shumaila& Umer, Nigarish& Shabbir, Arham& Shafiq-ur-Rehman, Arham…[et al.]. Nyctanthes arbor-tristis Ameliorated FCA-Induced Experimental Arthritis: A Comparative Study among Different Extracts. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1153819
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153819
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)