A Simplified Diagnostic Classification Scheme of Chemotherapy-Induced Peripheral Neuropathy
المؤلفون المشاركون
Lin, Chou-Ching K.
Wu, Pei-Ying
Su, Pei-Fang
Li, Chung-I
Yeh, Yu-Min
Lin, Peng-Chan
Hsu, Keng-Fu
Shen, Meng-Ru
Chang, Jang-Yang
Huang, Han-Wei
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background and Objective.
The main purpose of this study was to develop a simple automatic diagnostic classification scheme for chemotherapy-induced peripheral neuropathy.
Methods.
This was a prospective cohort study that enrolled patients with colorectal or gynecologic cancer post chemotherapy for more than 1 year.
The patients underwent laboratory examinations (nerve conduction studies and quantitative sensory tests), and a questionnaire about the quality of life.
An unsupervised classification algorithm was used to classify the patients into groups using a small number of variables derived from the laboratory tests.
A panel of five neurologists also diagnosed the types of neuropathies according to the laboratory tests.
The results by the unsupervised classification algorithm and the neurologists were compared.
Results.
The neurologists’ diagnoses showed much higher rates of entrapment syndromes (66.1%) and radiculopathies (55.1%) than polyneuropathy (motor/sensory: 33.1%/29.7%).
A multivariate analysis showed that the questionnaire was not significantly correlated with the results of quantitative sensory tests (r=0.27) or the neurologists’ diagnoses (r=0.2).
All of the patients were classified into four groups by the unsupervised classification algorithm.
The classification corresponded to the severity of neuropathy and correlated well with the neurologists’ diagnoses and the scales of neurological examinations.
The overall correct rate of classification by the unsupervised classification algorithm was 78.8% (95% confidence interval: 73.1%-88.3%).
Conclusion.
The results of our unsupervised classification algorithm based on three variables of laboratory tests correlated well with the neurologists’ diagnoses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Han-Wei& Wu, Pei-Ying& Su, Pei-Fang& Li, Chung-I& Yeh, Yu-Min& Lin, Peng-Chan…[et al.]. 2020. A Simplified Diagnostic Classification Scheme of Chemotherapy-Induced Peripheral Neuropathy. Disease Markers،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1153820
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Han-Wei…[et al.]. A Simplified Diagnostic Classification Scheme of Chemotherapy-Induced Peripheral Neuropathy. Disease Markers No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1153820
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Han-Wei& Wu, Pei-Ying& Su, Pei-Fang& Li, Chung-I& Yeh, Yu-Min& Lin, Peng-Chan…[et al.]. A Simplified Diagnostic Classification Scheme of Chemotherapy-Induced Peripheral Neuropathy. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1153820
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153820
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر